Zenrelia (Ilunocitinib Tablets) Once Daily Prescription Itch Relief for Dogs

What is Zenrelia (Ilunocitinib Tablets) Once Daily Prescription Itch Relief for Dogs?

Zenrelia is an innovative, once-daily treatment that offers relief from itchy, irritated skin – right from the start. Allergic dermatitis can make your dog very uncomfortable. Symptoms like excessive itching, scratching, and biting aren't only disruptive to you and your pet, but they can also cause more severe problems over time, including hair loss and skin infection. Don’t let allergic itch disrupt your dog’s Zen. Reach for Zenrelia.

Suitable for:

Dogs at least 12 months of age.

Benefits

• Zenrelia relieves itching in dogs due to allergic dermatitis and controls atopic dermatitis.
• Zenrelia can get your dog back to normal**, with visible signs of itch relief on day 1 (**Data on file **Clinical remission of itch demonstrated by a Normal-PVAS<2)
• Ilunocitinib, the active ingredient in Zenrelia, works by reducing the itch and inflammatory response in your dog's skin due to allergies.
• The most common side effects reported with this dog dermatitis treatment were vomiting, diarrhea and tiredness; please see product insert for more information.
• The once-daily hypoallergenic unflavored tablet can be given with or without food from the comfort of your home.
• No need to load or taper dose: can stop/start for short or long-term use. 

Brand Name:

Zenrelia

Generic Name:

Ilunocitinib Tablets

How does Zenrelia (Ilunocitinib Tablets) Once Daily Prescription Itch Relief for Dogs work?

Zenrelia blocks itch signals from reaching your dog’s brain, reducing the sensation of itch. The active ingredient, ilunocitinib, reduces the inflammatory response in your dog's skin caused by allergies. The result? Red and inflamed skin is soothed, and your dog’s itchiness goes back to just the normal, occasional good scratch. In fact, dogs may have visible signs of itch relief on day 1*. What's more, Zenrelia is designed to deliver continuous efficacy over the long term and can get your dog back to normal**.  Ask your veterinarian if Zenrelia can relieve itching in your dog due to allergic and atopic dermatitis. Fast relief for your best friend is also a relief for you. Spend more time doing the things you love, like cuddling and playing, and less time managing your dog's allergy symptoms.(*Data on file **Clinical remission of itch demonstrated by a Normal-PVAS<2)

What is the most important information I should know about Zenrelia (Ilunocitinib Tablets) Once Daily Prescription Itch Relief for Dogs?

Vaccination Precautions: Zenrelia carries a boxed warning regarding vaccination. Dogs should not receive vaccines during treatment due to risks of fatal vaccine-induced disease and inadequate immune response. It's recommended to discontinue Zenrelia for at least 28 days to 3 months before vaccination and withhold it for at least 28 days after vaccination. Ensure your dog is up to date on vaccinations prior to starting Zenrelia.

Age and Health Restrictions: Zenrelia is not approved for use in dogs under 12 months old or those with serious infections. Its safety has not been evaluated in breeding, pregnant, or lactating dogs.

What should I discuss with my veterinarian before giving Zenrelia (Ilunocitinib Tablets) Once Daily Prescription Itch Relief for Dogs to my pet?

Before giving Zenrelia (Ilunocitinib Tablets) to your dog discuss any existing health conditions. Inform your vet if your dog has any infections, a history of immune system disorders, or other chronic illnesses. Zenrelia is contraindicated in dogs with serious infections. Discuss your dog's vaccination status and concerns with your Veterinarian. Dogs should not be vaccinated while on Zenrelia due to risks of vaccine-induced diseases and a weakened immune response. Ensure your dog is fully vaccinated before starting Zenrelia. Ask about the timing of vaccinations relative to starting or stopping Zenrelia (e.g., wait 28 days to 3 months before restarting vaccinations after treatment). Zenrelia has not been tested for safety in breeding, pregnant, or lactating dogs. If your dog is in one of these categories, discuss alternative treatments.

What happens if I overdose my pet on Zenrelia (Ilunocitinib Tablets) Once Daily Prescription Itch Relief for Dogs ?

If your dog is accidentally overdosed on Zenrelia (Ilunocitinib Tablets), they may experience an increased risk of side effects such as severe vomiting, diarrhea, lethargy, loss of appetite, or signs of infection due to immune suppression. Overdose could also heighten the likelihood of more serious complications, including increased susceptibility to opportunistic infections or adverse effects on organ systems. Contact your veterinarian or an emergency pet poison control center immediately for guidance. Bring the medication packaging with you to provide accurate information about the dosage.

How should Zenrelia (Ilunocitinib Tablets) Once Daily Prescription Itch Relief for Dogs be given/administered?

Administer once daily as directed by your veterinarian. The specific dosage will depend on your dog's weight and condition. Zenrelia can typically be given with or without food, but follow your veterinarian's recommendation for optimal absorption. Give the tablet at the same time each day to maintain consistent blood levels of the medication.

What happens if I miss giving a dose of Zenrelia (Ilunocitinib Tablets) Once Daily Prescription Itch Relief for Dogs?

Do not give extra doses or double up if a dose is missed. Administer the next dose as scheduled.

What should I avoid while giving Zenrelia (Ilunocitinib Tablets) Once Daily Prescription Itch Relief for Dogs?

Do not vaccinate your dog while they are on Zenrelia. The medication suppresses the immune system, which can lead to:
fatal vaccine-induced diseases or reduced effectiveness of vaccines. Wait 28 days to 3 months after stopping Zenrelia before vaccinating. 

What other drugs will affect Zenrelia (Ilunocitinib Tablets) Once Daily Prescription Itch Relief for Dogs?

Avoid combining Zenrelia with Glucocorticoids (e.g., prednisone), Cyclosporine, or other Immunosuppressive Drugs unless specifically directed by your Veterinarian.

What are the possible side effects of Zenrelia (Ilunocitinib Tablets) Once Daily Prescription Itch Relief for Dogs?

Common side effects include vomiting, diarrhea, and lethargy. Discuss how to manage these if they occur.

Cautions:

Do not administer vaccines to a dog receiving Zenrelia. Discontinue use of Zenrelia at least 28 days to 3 months prior to vaccination and withhold administration of Zenrelia for at least 28 days after vaccination. Zenrelia may increase susceptibility to or exacerbate subclinical or uncomplicated infections, including demodicosis and pneumonia. Zenrelia is not for use in dogs with serious infections or in dogs less than 12 months of age.New neoplastic conditions (benign and malignant) were observed in dogs treated with Zenrelia during clinical studies.Keep Zenrelia in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.Wash hands immediately after handling tablets. In case of accidental ingestion, seek medical attention immediately.

Storage:

Store at room temperature between 15 to 25°C (59 to 77°F).