Sentinel - Heartworm + Broad Spectrum Prevention Chewable Tablet for Dogs

What is Sentinel Flavor Tabs?

Sentinel Flavor Tabs are a once monthly oral preventive that guards against heartworms, adult roundworms, adult hookworms, whipworms, and prevents the development of flea eggs. Sentinel Flavor Tabs requires a prescription from your veterinarian.

Suitable For:

Dogs and Puppies (4+ weeks of age, weighing 2+ lbs)

Benefits:

• Sentinel Flavor Tabs come in a convenient and effective once-a-month dose, in a delicious pork liver flavored tablet
• Dogs love the taste, making administration easy and convenient
• Unique to Sentinel brand products, lufenuron stops flea eggs from hatching.
• Sentinel Flavor Tabs have been shown to be safe for puppies as young as 4 weeks of age.
• Provides broad-spectrum protection against 5 types of parasites including:
  • Heartworms: milbemycin oxime prevents heartworm disease.
  • Hookworms: milbemycin oxime treats and controls adult hookworms.
  • Roundworms: milbemycin oxime treats and controls adult roundworms.
  • Whipworms: milbemycin oxime treats and controls adult whipworms.
  • Immature Fleas: lufenuron prevents and controls flea populations

How does Sentinel Flavor Tabs work?

Milbemycin oxime eliminates the tissue stage of heartworm larvae and the adult stage of hookworm, roundworm, and whipworm infestations. Lufenuron, the other active ingredient, is an insect development inhibitor that breaks the flea life cycle by inhibiting egg development. Lufenuron prevents most flea eggs from hatching or maturing into adults and thus prevents and controls flea populations by breaking the life cycle.

Cautions:

Not for human use. Keep this and all drugs out of the reach of children. Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. Do not use in puppies less than four weeks of age and less than two pounds of body weight. Prior to administration of Sentinel Flavor Tabs, dogs should be tested for existing heartworm infections. Infected dogs should be treated to remove adult heartworms and microfilariae prior to initiating treatment with Sentinel Flavor Tabs. Mild, transient hypersensitivity reactions manifested as labored respiration, vomiting, salivation and lethargy have been noted in some treated dogs carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae. It's also important to eliminate fleas and to not feed your pet rodents or uncooked meat or fish. To prevent re-infection, clean up stools on a daily basis. Consult your veterinarian for pregnant or lactating dogs.

Brand Name:

Sentinel Flavor Tabs (Merck)

Generic Name:

Milbemycin Oxime (mil-beh-my-sin ox-eem) and Lufenuron (lew-fen-your-on)

What is the most important information I should know about Sentinel Flavor Tabs?

Sentinel Flavor Tabs is a prescription medication FDA-approved for use in dogs. Sentinel Flavor Tabs is available as artificial beef flavored (derived from pork and soy protein) chewable tablets. This medication should be given once a month year-round.

What should I discuss with my veterinarian before giving Sentinel Flavor Tabs to my pet?

Tell your veterinarian if your pet has ever had an allergic reaction to the medication.

How should Sentinel Flavor Tabs be given?

Give Sentinel Flavor Tabs exactly as directed by your veterinarian. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. The usual dose of Sentinel Flavor Tabs for dogs 2 to 10 pounds is 1 Flavor Tab every month (Brown Box), 11 to 25 pounds is 1 Flavor Tab every month (Green Box), 26 to 50 pounds is 1 Flavor Tab every month (Yellow Box) and 51 to 100 pounds is 1 Flavor Tab every month (White Box). For dogs over 100 pounds give the appropriate combination of tablets. To ensure adequate absorption, always administer Sentinel Flavor Tabs to dogs immediately after or in conjunction with a normal meal. Heartworm testing should be performed prior to the start of prevention therapy. If your pet is off Sentinel Flavor Tabs for 6 months or less, re-start the medication and test after 6 months since microfilaria, that take 6 months to mature, will result in a positive test result. Store Sentinel Flavor Tabs in a dry place at controlled room temperature, between 59-77F (15-25 C). Do not remove the tablet from its wrapper until ready to give the medicine. Keep this medication away from children and pets. Consult your veterinarian for pregnant or lactating dogs.

What are the possible side effects of Sentinel Flavor Tabs?

The following adverse reactions have been reported in dogs after giving milbemycin oxime or lufenuron: vomiting, depression/lethargy, pruritus, urticaria, diarrhea, anorexia, skin congestion, ataxia, convulsions, hypersalivation, and weakness. 

What happens if I miss giving a dose of Sentinel Flavor Tabs?

If a dose is missed and a 30-day interval between dosing is exceeded, administer Sentinel Flavor Tabs immediately and resume the monthly dosing schedule. If Sentinel Flavor Tabs replaces daily diethylcarbamazine (DEC) for heartworm prevention, the first dose must be given within 30 days after the last dose of DEC.

What happens if I overdose my pet on Sentinel Flavor Tabs?

Contact your veterinarian immediately.

What should I avoid while giving Sentinel Flavor Tabs to my pet?

Because humans can contract hookworms and roundworms from pets, it is important to maintain good personal hygiene. It is also important to eliminate fleas on your pet and in the household.

What other drugs will affect Sentinel Flavor Tabs?

While Sentinel Flavor Tabs is safe to use in dogs at risk for MDRI-allele mutation (Australian Shepherds, Collies, Shelties, etc.), unless tested normal, caution is advised if your pet is also being given amiodarone (Cordarone), azole antifungals such as ketoconazole, carvedilol (Coreg), cyclosporine (Atopica), diltiazem (Cardizem), erythromycin (Ery-Tabs) or clarithromycin (Biaxin), quinidine, spironolactone (Aldactone), tamoxifen, and verapamil (Calan). Do not give Sentinel Flavor Tabs to your pet if already giving an alternate heartworm medication.

Storage:

Store in a dry place at controlled room temperature, between 59° and 77° F.