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Kills Fleas |
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Repels Fleas |
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Kills Flea eggs and Larvae |
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Kills Ticks |
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Repels Ticks |
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Kills and/or Repels Mosquitoes |
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Prevents Heartworm |
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Other Parasites Information | Eliminates infestations with chewing lice, aids in the control of sarcoptic mange infestation | Kills chewing lice in dogs and puppies and controls mites that may cause sarcoptic mange. |
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Waterproof (shampooing once a week can reduce effectiveness) |
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N/A |
Safe for pregnant or nursing Pets |
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The safe use of Simparica has not been evaluated in breeding, pregnant, or lactating dogs. |
How long does it take to work | Kills Fleas within 12 hours and Ticks within 48 hours | Kills fleas and ticks with the same efficacy as Frontline Top Spot. | Begins to kill adult fleas within 3 hours and ticks within 8 hours of administration. |
Taste | Applied to Skin | Applied to Skin | Liver flavor |
Active Ingredient(s) | Fipronil/(S)-Methoprene | Fipronil | sarolaner |
RX Required |
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Dosage | Monthly | ||
Usage |
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Video | Coming soon | Coming soon | Coming soon |
Vet Review | I find that the effective combination of an ingredient like fipronil, along with the insect growth regulator methoprene, provides the best spectrum of activity and protection against all stages of the flea life cycle from egg through larval stage on to adult. Because of these two main ingredients and their method of action, I find that clients don't have to treat the environment as much. I find that this product tends to be safer in smaller breed animals when compared to its competition. I find its tick efficacy quite good. The fact that it is waterproof also allows clients, whose pets swim frequently, to confidently use this product during the swimming months. I also find that this product works the longest for fleas, while some of the competitive products have to be reapplied before the end of the month. The lack of label efficacy against mosquitoes and flies, as well as the fact that this product does not repel fleas or ticks are the two main disadvantages. As with any insecticidal products, I find that every pet is an individual, in terms of which of the products works best on them. When I am dealing with more of a flea issue in a patient, this is the product I will likely reach for first. | This product is a wonderful economic alternative for clients who have used the Frontline product. It contains the same exact main ingredient as Frontline, Fipronil, which has been probably the number one used flea and tick preventative ingredient by veterinarians over decades now. Not only does it kill fleas and many species of ticks that carry Lyme and other diseases, but also can help in controlling scabies mange mites, as well, in those cases. It certainly is a much cheaper alternative to Frontline or Advantage products. Some excellent advantages include it being waterproof, as well as being safe to use in pets as young as 8 weeks of age. There may be a rare skin irritation side effect at the site of application, but other reactions are even more rare. I have occasionally seen digestive upset with this product. I would also not use it in dogs with a history of chronic seizure disorders. Because of its long-term reliability and safety, I give this product an overall rating of a 4.5, with an ease of application of 4.5. | Within the past few years, we have seen a surge of new flea and tick parasiticides for dogs and cats, especially important as we are discovering increased transmission of health-threatening disease to our animal companions. In the past year, the very trustworthy and reliable pharmaceutical company Zoetis has come out with a revolutionary liver flavored chewable tablet, Simparica, that is highly effective against fleas and multiple species of ticks. Compared to similar oral tablets, as well as other topical products, I find that Simparica works even more quickly than competitor products, starting to kill fleas within 3 hours, and ticks within 8 hours. Unlike other products labeled for monthly use, studies and my clinical experience show that Simparica is actually effective up to 35 days, not dropping off in efficacy as many other products do in killing fleas and ticks toward the end of the month. I also find that the many flexible dosing packages offer convenience to canine guardians, even in small dogs who weigh under 5 pounds. In addition to the efficacy against fleas and ticks, the product is also labeled effective against scabies mites. Many veterinarians and dermatologists are also now reaching for Simparica as a quick, safe and effective off-label treatment of demodex mange mites, which have long been very difficult to manage in veterinary medicine. I have found that in many cases one dose of Simparica will clear up many demodex mange cases within one month of the first pill. I have found that most dogs tolerate this product very well, especially when given with food. I have occasionally seen mild digestive upset in some sensitive pets, as well as rare neurological reactions. If a dog has a history of seizures, I would probably be cautious in using this product or ones of a similar class. Most dogs readily take this chewable tablet. I give this product an overall rating of a 4.5, with an efficacy of 4.5, and ease of use a 4.5. |