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Kills Fleas |
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Repels Fleas |
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Kills Flea eggs and Larvae |
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Prevents Development |
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Kills Ticks |
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Repels Ticks |
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Kills and/or Repels Mosquitoes |
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Prevents Heartworm |
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Other Parasites Information |
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Controls adult hookworms and removes and controls adult roundworms & whipworms |
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Waterproof (shampooing once a week can reduce effectiveness) | Not Applicable | N/A | N/A |
Safe for pregnant or nursing Pets |
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The safe use of Simparica has not been evaluated in breeding, pregnant, or lactating dogs. |
How long does it take to work | Kills fleas in 30 minutes. | Begins to work Immediately, However, pre-existing flea populations may continue to develop and emerge. | Begins to kill adult fleas within 3 hours and ticks within 8 hours of administration. |
Taste | Unflavored Tablet | Beef Flavor | Liver flavor |
Active Ingredient(s) | Nitenpyram | Milbemycin Oxime/Lufenuron | sarolaner |
RX Required |
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Dosage | |||
Usage |
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Video | Coming soon | Coming soon | Coming soon |
Vet Review | This is a wonderful quick kill short duration flea adulticide that begins killing adult fleas within 30 minutes. It does not leave pesticide residue on the pet or in the home, and when combined with its sister product Program, offers an excellent non-pesticidal alternative for all around flea control to topical pesticides that some clients are concerned about. I have rarely seen any side effects in my clinical experience in using this product. I have used it up to once daily in flea infested animals, but more commonly I use it once or twice weekly during flea transmission season along with the once monthly Program product. Another wonderful advantage of this product is its safety in administering it to pregnant or nursing dogs, who can often be a big source of fleas to their nursing puppies or kittens. The biggest disadvantage to this product is that it only kills adult fleas, but this problem is easily circumvented by combining it with the Program product. | Sentinel is a wonderful combination of the heartworm prevention pill interceptor and the flea control product program both in this one pill. Many clients enjoy the convenience of having such broad acting internal and external parasites in one pill, without having to worry about giving two separate medicines. Lufenuron, which is the main flea control ingredient, stops the flea life cycle in its track at the egg and larval stage, thus being like a birth control pill for fleas who get on our pets. Given that the main problem of fleas is how rapidly they reproduce, this pill literally stops escalating growth of flea populations, before they can become established in our homes, where most of the flea life cycle occurs. The main disadvantage to this product is that it does not kill or repel adult fleas, so in situations with already established heavy infestations, it is best combined with a great topical product like advantage or front line or with the oral adulticide flea pill Capstar for maximal effect. The only other rare disadvantage I see is the slight increase in reactions when two products are combined into one like this, but fortunately this is not common in clinical practice. With milbemycin for prevention of heartworms and controlling and treating most common intestinal worms, I overall highly recommend this versatile product. | Within the past few years, we have seen a surge of new flea and tick parasiticides for dogs and cats, especially important as we are discovering increased transmission of health-threatening disease to our animal companions. In the past year, the very trustworthy and reliable pharmaceutical company Zoetis has come out with a revolutionary liver flavored chewable tablet, Simparica, that is highly effective against fleas and multiple species of ticks. Compared to similar oral tablets, as well as other topical products, I find that Simparica works even more quickly than competitor products, starting to kill fleas within 3 hours, and ticks within 8 hours. Unlike other products labeled for monthly use, studies and my clinical experience show that Simparica is actually effective up to 35 days, not dropping off in efficacy as many other products do in killing fleas and ticks toward the end of the month. I also find that the many flexible dosing packages offer convenience to canine guardians, even in small dogs who weigh under 5 pounds. In addition to the efficacy against fleas and ticks, the product is also labeled effective against scabies mites. Many veterinarians and dermatologists are also now reaching for Simparica as a quick, safe and effective off-label treatment of demodex mange mites, which have long been very difficult to manage in veterinary medicine. I have found that in many cases one dose of Simparica will clear up many demodex mange cases within one month of the first pill. I have found that most dogs tolerate this product very well, especially when given with food. I have occasionally seen mild digestive upset in some sensitive pets, as well as rare neurological reactions. If a dog has a history of seizures, I would probably be cautious in using this product or ones of a similar class. Most dogs readily take this chewable tablet. I give this product an overall rating of a 4.5, with an efficacy of 4.5, and ease of use a 4.5. |