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Kills Fleas |
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Repels Fleas |
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Kills Flea eggs and Larvae |
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Kills fleas before they can lay eggs | Prevents Development |
Kills Ticks |
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Repels Ticks |
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Kills and/or Repels Mosquitoes |
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Prevents Heartworm |
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Other Parasites Information | NA |
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Controls adult hookworms and removes and controls adult roundworms & whipworms |
Waterproof (shampooing once a week can reduce effectiveness) |
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N/A | N/A |
Safe for pregnant or nursing Pets |
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The safe use of NexGard in pregnant, breeding or lactating dogs has not been evaluated. |
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How long does it take to work | Reapply Activyl every 30 days. | NexGard kills 100% of fleas within 24 hours. | Begins to work Immediately, However, pre-existing flea populations may continue to develop and emerge. |
Taste | Applied to skin | Beef-flavored chewable | Beef Flavor |
Active Ingredient(s) | indoxacarb | Afoxolaner | Milbemycin Oxime/Lufenuron |
RX Required |
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Dosage | |||
Usage |
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Video | Coming soon | Coming soon | Coming soon |
Vet Review | Another recently available new topical flea preventative for dogs and cats. This new product works by being activated by only the flea's enzyme systems into a flea specific mechanism which paralyzes and kills the adult flea. The company claims that it does not get into the blood stream, but stays only in the superficial skin layers of the pet. Any adult fleas which come into contact with this product are quickly killed so that fleas do not have to actually bite the pet, which is tremendously helpful in those flea-allergic pets, where it only takes a few flea bites to set off an extensive itchy allergic reaction. Another wonderful benefit of this product is that it is waterproof, which is especially helpful in those active outside pets who are exposed to rain or like to swim. This effective product starts working within 12 hours of application, where over 90% of adult fleas are killed. Another excellent benefit of this product is that it also inhibits the development of flea eggs and larvae in the environment, which is a big bonus since much of the flea life cycle occurs in the home environment. While Activyl is very safe and effective for most pets, I have seen occasional rare reactions in sensitive pets, which most commonly is seen as irritation or excessive itchiness at the site of application. While the company says that it is odorless, some of my clients have said that they do sense an odor within the first several days of application, as well as leaving an occasional oily film for the first day or two following application. This film, however usually quickly disappears. The only other very rare reactions include digestive upset and/or drooling/neurological reactions, and certainly if a pet has any chronic digestive weaknesses or history of seizures, etc then the local veterinarian should be consulted before applying the product. I give this product an overall rating of 4, with an ease of use of 4. | Within the past year there has been an exciting development in the battle against fleas and ticks.For years, veterinarians have relied on topical medications for control of fleas and ticks, however many formulations are greasy, as well as some sensitive pets may have an allergic reaction to contact some of them. Many clients also worry about the exposure of humans to topical flea and tick pesticides. That is why the exciting new product from Merial known as Nexgard has been such a welcome addition to our flea and tick treatment and prevention options. By using a the ingredient, afoxolaner, Merial has come out with a new product that most fleas and ticks are certainly susceptible. Dogs also LOVE the soft, beef flavored chewable, even without meals. It has also been shown to be safe at up to 5 times the recommended dose.The only down side to this product is that the parasites must bite the dog to be affected, and in some cases this may take up to many hours for this to occur. However, studies as well as clinical experience with this product show that is it very effective in preventing Lyme, Anaplasmosis, Ehrlichiosis and Rocky Mountain spotted fever. This makes it essential as part of any year round parasite prevention program in our dogs. The only rare side effects I have seen are mild digestive upset. I therefore give this product an overall rating of a 4.5, with an ease of use of a 5 out of 5. | Sentinel is a wonderful combination of the heartworm prevention pill interceptor and the flea control product program both in this one pill. Many clients enjoy the convenience of having such broad acting internal and external parasites in one pill, without having to worry about giving two separate medicines. Lufenuron, which is the main flea control ingredient, stops the flea life cycle in its track at the egg and larval stage, thus being like a birth control pill for fleas who get on our pets. Given that the main problem of fleas is how rapidly they reproduce, this pill literally stops escalating growth of flea populations, before they can become established in our homes, where most of the flea life cycle occurs. The main disadvantage to this product is that it does not kill or repel adult fleas, so in situations with already established heavy infestations, it is best combined with a great topical product like advantage or front line or with the oral adulticide flea pill Capstar for maximal effect. The only other rare disadvantage I see is the slight increase in reactions when two products are combined into one like this, but fortunately this is not common in clinical practice. With milbemycin for prevention of heartworms and controlling and treating most common intestinal worms, I overall highly recommend this versatile product. |