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Kills Fleas |
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Repels Fleas |
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Kills Flea eggs and Larvae | Prevents Development | Prevents development | Prevents Development |
Kills Ticks |
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Repels Ticks |
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Kills and/or Repels Mosquitoes |
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Prevents Heartworm |
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Other Parasites Information | Chewing lice for up to 30 days. | Controls ear mites, roundworms and hookworms. | Controls adult hookworms and removes and controls adult roundworms & whipworms |
Waterproof (shampooing once a week can reduce effectiveness) |
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N/A |
Safe for pregnant or nursing Pets |
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How long does it take to work | Starts working in 1 hour | See a greater than 90% control of your flea infestation during the first month but because adult fleas will emerge from cocoons in your environment, you may see a few fleas for several months until the flea population is destroyed. | Begins to work Immediately, However, pre-existing flea populations may continue to develop and emerge. |
Taste | Applied to skin | Applied to Skin | Beef Flavor |
Active Ingredient(s) | Fipronil | Selamectin | Milbemycin Oxime/Lufenuron |
RX Required |
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Dosage | |||
Usage |
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Video | Coming soon | Coming soon | Coming soon |
Vet Review | This reliable and more economical alternative to Frontline comes from a very reliable company, Elanco. Its main ingredient, fipronil, probably has the most clinical record of experience of efficacy over many years, in killing both adult fleas before they lay eggs, as well as various species of ticks. Its safety is touted by supposedly targeting only the nervous system of the pests. With cats, we always must be careful when evaluating the newer generation of emerging pesticides for fleas and ticks that are coming out, as kitties' detoxification pathways are typically more sensitive than dogs'. Most kitties tolerate this single spot application quite well. In addition to being waterproof, so important for outdoor kitties, this product is easier to apply than most competitors, as well as leaving no pungent or chemical smell like many over the counter competitor products. Most of my clients have found it as effective as Frontline, but not as quick as Advantage. Some clients have complained that it does not seem to repel the ticks, who can occasionally be found attached to the skin before they die. Not only it is important in using products like Easy Spot to prevent flea bite anemia in cats, and unsightly tapeworms, but in recent years, fleas have been shown to carry an increasing number of serious diseases and infections, including Bartonella species, amongst others. Another benefit of this product is that it is labeled as safe to use in pregnant or nursing cats. Side effects, although rare, may include topical irritation at the site of application, lethargy, as well as rare twitching reactions, agitation, and/or restlessness. These are typically short-lived, and fortunately, are very uncommon across pet populations that the product has been used. Some veterinarians and experts have wondered about the recent resistance of fleas to some of the fipronil-based products, but that has not been my experience. I give this product an overall rating of a 4, with an ease of application and efficacy of 4, as well. | This versatile topical product has the widest range of protection of both internal and external parasites. In both cats and dogs, all 3 stages of the flea life cycle are effectively controlled,in addition to ear mites. For dogs, there is also the wonderful treatment benefit of killing hidden scabies mites on the skin, which are so difficult for veterinarians to find on routine skin scrapings at our offices. In fact, when either I or veterinary dermatologists are presented with a very itchy dog, in addition to our allergy workups, we will often treat with this topical every few weeks to treat and rule out any hidden scabies mites contributing to the pet's itching. It is amazing how many dogs will respond to this treatment, leading me to believe that scabies mites are involved with a lot more itching problems in dogs than I first learned about in vet school. With the increased recognition and understanding of feline heartworm disease, this is often the first heartworm preventative that I will reach for in cats, especially given all of the other benefits above. While it is often effective for canine heartworm prevention as well, I have heard of rare lapses in protection, so I usually combine this topical in dogs with one of the oral heartworm prevention medications like Heartgard or Interceptor. The only disadvantage I have seen is the rare reaction on cats of mild digestive upset and temporary hair loss at the site of application. It also has the wonderful benefits of being water proof in only 2 hours after application, and in being approved for use in puppies as young as 6 weeks of age. | Sentinel is a wonderful combination of the heartworm prevention pill interceptor and the flea control product program both in this one pill. Many clients enjoy the convenience of having such broad acting internal and external parasites in one pill, without having to worry about giving two separate medicines. Lufenuron, which is the main flea control ingredient, stops the flea life cycle in its track at the egg and larval stage, thus being like a birth control pill for fleas who get on our pets. Given that the main problem of fleas is how rapidly they reproduce, this pill literally stops escalating growth of flea populations, before they can become established in our homes, where most of the flea life cycle occurs. The main disadvantage to this product is that it does not kill or repel adult fleas, so in situations with already established heavy infestations, it is best combined with a great topical product like advantage or front line or with the oral adulticide flea pill Capstar for maximal effect. The only other rare disadvantage I see is the slight increase in reactions when two products are combined into one like this, but fortunately this is not common in clinical practice. With milbemycin for prevention of heartworms and controlling and treating most common intestinal worms, I overall highly recommend this versatile product. |