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| Kills Fleas |
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| Repels Fleas |
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| Kills Flea eggs and Larvae |
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Kills fleas before they lay eggs |
| Kills Ticks |
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| Repels Ticks |
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| Kills and/or Repels Mosquitoes |
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| Prevents Heartworm |
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| Other Parasites Information | Controls ear mites, hookworms and roundworms. | Advantage XD kills lice, but does not treat any internal parasites like heartworms or intestinal worms. | Treats and controls ear mites, roundworms, and hookworms. |
| Waterproof (shampooing once a week can reduce effectiveness) |
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Yes, Advantage XD is waterproof. Do not bathe your cat or allow them to get wet for at least 24 hours after applying Advantage® XD. Frequent shampooing can reduce effectiveness. See product label for more information. | N/A |
| Safe for pregnant or nursing Pets | Consult your veterinarian | Consult your veterinarian for pregnant or nursing cats. | The safe use of Revolution Plus in pregnant, breeding or lactating cats has not been evaluated. |
| How long does it take to work | Kills fleas within 12 hours. | 30 minutes to 4 hours. | Starts killing fleas within 6 hours |
| Taste | Applied To Skin | Not applicable (topical treatment). | Applied to skin |
| Active Ingredient(s) | Imidacloprid/Moxidectin | Spinetoram | Selamectin, Sarolaner |
| RX Required |
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| Dosage | Apply one applicator every 2 months. | ||
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| Video | Coming soon | Coming soon | Coming soon |
| Vet Review | By combining imidacloprid and moxidectin, Advantage Multi offers the wonderful benefit of broad protection against BOTH common internal and external parasites in dogs and cats. An important area of coverage includes not only adult stages, but the immature stages of roundworms and hookworms, two parasites that are a risk to people if not prevented in our pets. It also treats and controls, and prevents whipworms, which are difficult to eradicate in both dogs and the environment. When applied monthly, it is almost 100 percent effective in preventing heartworm disease in dogs and cats. Additional benefits of treating scabies and demodectic mange and ear mites make this a very attractive product. All of this with the wonderful flea control benefits of the product advantage. The greatest benefit I see with this versatile product is that it takes the labor out of administering a myriad of medications to dogs to control these varied internal and external parasites. I also find that it kills the larval stages of fleas in the home surroundings of treated pets, which is a wonderful added benefit. I have on rare occasions seen topical irritation and sensitivity at the site of application, and even more scarce neurological reactions in hypersensitive pets. The only other downside would be the potential high cost of this product, as well as the need for clients to obtain a prescription from their veterinarian. Overall, however, I have found this product to be an excellent and safe all around internal and external parasite control manager in our dogs and cats. |
The fast-acting nature of Advantage XD is one of its standout features, as it starts killing fleas within 30 minutes to 4 hours, providing rapid relief for cats. Its long-lasting formula is another major benefit, offering protection for up to two months per application, which is twice the duration of many other flea treatments. The active ingredient, spinetoram, is derived from natural soil microbes, making it a preferred option for veterinarians concerned about using harsh chemicals on sensitive pets. However, as with any topical treatment, some cats may experience mild skin reactions like irritation or hair loss at the application site. Despite this, Advantage XD remains a top choice for its effectiveness and ease of use, though in cases of severe infestations, veterinarians may recommend additional environmental flea control measures. |
A significant limitation of the original revolution product for cats is that it did not cover any species of ticks, which is especially important in those cats who go outside and/or live with dogs where there is increased chance of tick borne infections such as Lyme disease, Ehrlichia and Anaplasmosis in dogs, not to mention the risk of tick born disease exposure in people whose cats bring ticks in to the home. With this new formulation clients get protection against 3 species of ticks. The American Heartworm Society has published that one in 4 cats diagnosed with heartworm disease are indoor only cats, so that especially in Southern, warmer clients, heartworm disease prevention may become as important in cats as dogs. And it takes only a few heartworms to cause significant disease in cats, who seem much more sensitive on exposure to this parasite than even dogs are. This versatile product not only kills fleas before they eggs, but gives additional 6 in 1 protection again ticks, round worms, hookworms, as well as ear mites. THe product is quite quick drying, easy to apply, and not messy or greasy like many other topical formulations. The only down side as to efficacy is in those cases where there is a severe flea infestation affecting multiple animals in a household, where I have found some of the other products a bit more effective in those cases in both dogs and cats, however the vast majority of flea infestations are easily taken care of with this product. Because of the addition of the Sarolamer ingredient for tick control, I would not use this product if there is any history of neurological disease or seizures in the cat. The only other rare side effect I have seen is lethargy and because of its easy to use formulation, only very rare contact sensitivity. With all this being said, I give this product an overall rating of a 4 out of 5 with an ease of application of 5. |
Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors.
The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
Note: Any trademarks are the property of their respective companies.
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