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| Kills Fleas |
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| Repels Fleas |
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| Kills Flea eggs and Larvae |
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Kills all existing fleas, flea eggs, and flea larvae within 6 hours | Kills adult fleas and prevents flea eggs from hatching. |
| Kills Ticks |
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| Repels Ticks |
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| Kills and/or Repels Mosquitoes |
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| Prevents Heartworm |
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| Other Parasites Information | Advantage XD kills lice, but does not treat any internal parasites like heartworms or intestinal worms. | Kills chewing lice | It kills adult fleas and prevents flea eggs from hatching for one month and is indicated for the prevention and control of flea infestations (Ctenocephalides felis), prevention of heartworm disease caused by Dirofilaria immitis, and the treatment and control of ear mite (Otodectes cynotis) infestations. Senergy is also indicated for the treatment and control of roundworm (Toxocara cati) and intestinal hookworm (Ancylostoma tubaeforme) infections in cats and dogs. |
| Waterproof (shampooing once a week can reduce effectiveness) | Yes, Advantage XD is waterproof. Do not bathe your cat or allow them to get wet for at least 24 hours after applying Advantage® XD. Frequent shampooing can reduce effectiveness. See product label for more information. |
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Bathing or shampooing your pet 2 or more hours after treatment will not reduce the effectiveness. |
| Safe for pregnant or nursing Pets | Consult your veterinarian for pregnant or nursing cats. |
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N/A |
| How long does it take to work | 30 minutes to 4 hours. | Kills fleas within 6 hours of application and achieves 97% efficacy within 3 hours. | See a greater than 90% control of your flea infestation during the first month but because adult fleas will emerge from cocoons in your environment, you may see a few fleas for several months until the flea population is destroyed. |
| Taste | Not applicable (topical treatment). | Applied to skin | N/A |
| Active Ingredient(s) | Spinetoram | Dinotefuran, Fipronil, and Pyriproxyfen | Selamectin |
| RX Required |
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| Dosage | Apply one applicator every 2 months. | Monthly | |
| Usage |
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| Video | Coming soon | Coming soon | Coming soon |
| Vet Review |
The fast-acting nature of Advantage XD is one of its standout features, as it starts killing fleas within 30 minutes to 4 hours, providing rapid relief for cats. Its long-lasting formula is another major benefit, offering protection for up to two months per application, which is twice the duration of many other flea treatments. The active ingredient, spinetoram, is derived from natural soil microbes, making it a preferred option for veterinarians concerned about using harsh chemicals on sensitive pets. However, as with any topical treatment, some cats may experience mild skin reactions like irritation or hair loss at the application site. Despite this, Advantage XD remains a top choice for its effectiveness and ease of use, though in cases of severe infestations, veterinarians may recommend additional environmental flea control measures. |
Coming soon. | Coming Soon |
Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors.
The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
Note: Any trademarks are the property of their respective companies.
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