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Kills Fleas |
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Repels Fleas |
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Kills Flea eggs and Larvae |
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N/A |
Kills Ticks |
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Repels Ticks |
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Kills and/or Repels Mosquitoes |
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Prevents Heartworm |
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Other Parasites Information |
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Protects against 5 types of ticks, roundworms, and hookworms | |
Waterproof (shampooing once a week can reduce effectiveness) | NA | N/A | N/A |
Safe for pregnant or nursing Pets | Consult with your veterinarian before using this product on debilitated, aged, pregnant or nursing animals. | The safe use of Simparica has not been evaluated in breeding, pregnant, or lactating dogs. | The safe use of Simparica TRIO has not been evaluated in breeding, pregnant, or lactating dogs. |
How long does it take to work | Starts killing fleas in 30 minutes, and kills 98-100% of fleas in 12 hours. | Begins to kill adult fleas within 3 hours and ticks within 8 hours of administration. | It starts to kill deer ticks within 8 hours, and fleas within 4 hours |
Taste | Topical application | Liver flavor | liver-flavored chewable tablet |
Active Ingredient(s) | Spinetoram | sarolaner | Sarolaner, moxidectin, and pyrantel |
RX Required |
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Dosage | Monthly | ||
Usage |
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Video | Coming soon | Coming soon | Coming soon |
Vet Review | Fleas are easily the most common external parasite that plague cats throughout the country. Fleas have been shown to not only cause weakness and anemia in affected cats, but also transmit dangerous infectious diseases, including bartonellosis, an also increasing threat to humans. Cheristin is made with the same main ingredient as Comfortis for cats, and acts uniquely on the nervous system of the flea. Unlike flea prevention tablets, Cheristin starts killing fleas within 30 minutes and almost 100 percent of fleas within 12 hours. With the easy to use applicator, this product has been shown to be quite effective for one month. The most common, yet rare side effect I have seen in cats is an allergic reaction or hair loss at the site of application, and even less commonly vomiting and lethargy. It is an excellent and fast acting, effective product with an overall rating of a 4.5 with an ease of administration of a 5. | Within the past few years, we have seen a surge of new flea and tick parasiticides for dogs and cats, especially important as we are discovering increased transmission of health-threatening disease to our animal companions. In the past year, the very trustworthy and reliable pharmaceutical company Zoetis has come out with a revolutionary liver flavored chewable tablet, Simparica, that is highly effective against fleas and multiple species of ticks. Compared to similar oral tablets, as well as other topical products, I find that Simparica works even more quickly than competitor products, starting to kill fleas within 3 hours, and ticks within 8 hours. Unlike other products labeled for monthly use, studies and my clinical experience show that Simparica is actually effective up to 35 days, not dropping off in efficacy as many other products do in killing fleas and ticks toward the end of the month. I also find that the many flexible dosing packages offer convenience to canine guardians, even in small dogs who weigh under 5 pounds. In addition to the efficacy against fleas and ticks, the product is also labeled effective against scabies mites. Many veterinarians and dermatologists are also now reaching for Simparica as a quick, safe and effective off-label treatment of demodex mange mites, which have long been very difficult to manage in veterinary medicine. I have found that in many cases one dose of Simparica will clear up many demodex mange cases within one month of the first pill. I have found that most dogs tolerate this product very well, especially when given with food. I have occasionally seen mild digestive upset in some sensitive pets, as well as rare neurological reactions. If a dog has a history of seizures, I would probably be cautious in using this product or ones of a similar class. Most dogs readily take this chewable tablet. I give this product an overall rating of a 4.5, with an efficacy of 4.5, and ease of use a 4.5. | Coming soon |