Flea5X Plus vs. Frontline Gold Comparison

Flea5X Plus

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Frontline Gold

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K9 Advantix II

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Kills Fleas

Repels Fleas

Kills Flea eggs and Larvae

Kills Ticks

Repels Ticks

Kills and/or Repels Mosquitoes

Prevents Heartworm

Other Parasites Information

Eliminates infestations with chewing lice, aids in the control of sarcoptic mange infestation

Eliminates infestations with chewing lice

Repels and prevents blood-feeding by biting flies and kills chewing lice.

Waterproof (shampooing once a week can reduce effectiveness)

Safe for pregnant or nursing Pets

Consult your veterinarian

How long does it take to work

Fast-acting protection that lasts up to 30 days

Starts killing fleas in 30 minutes

Kills Fleas 12 hours

Taste

Applied to skin

Applied to Skin

Active Ingredient(s)

Fipronil/(S)-Methoprene

Fipronil, S-methoprene, Pyriproxyfen

Imidacloprid/ Permethrin/Pyriproxyfen

RX Required

Dosage

Usage

Video

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Vet Review

1800petmeds is very excited to now offer an economic and reliable alternative to the brand name Front line plus in the war against flea and tick infestations on dogs and cats. By storing itself in the oil glands of the skin, the ingredients self distribute through the hair follicles and provide protection against fleas, ticks and lice for up to a month. While most of the competitors' products kill only the adult fleas on pets, the two main ingredients in this product, fiprinil and methoprene, not only kill the adult fleas and ticks, but also eggs and larvae, which may represent up to 95% of the total flea population. Recent studies in dogs have shown that these ingredients together start killing fleas within 4 hours, and within 12 to 24 hours 100% of the fleas are killed. While many competitors' products require the fleas to bite the pet, Flea 5x kills on contact. Another wonderful advantage of using Flea 5x is that the product is water proof, and will not be washed away with bathing or swimming, as long as animal guardians wait until the product is completely absorbed into the oil glands, which usually takes 48 hours, before bathing the pet or allowing pet to swim. Veterinarians and guardians should also know that this product is safe to use in breeding, pregnant and lactating dogs and cats. However kittens and puppies should be at least 8 weeks of age before applying this product. Because fleas and ticks pose many health threats to both dogs and cats, including dangerous anemia, rickettsial diseases, flea allergy dermatitis, and tapeworms, it is important to have all pets on a comprehensive flea and tick control program such as Flea 5x. And with the reliable 1800petmeds brand name, animal guardians can confidently rely on the performance of this product as comparable to the brand name. I see very few disadvantages in using this product. Rarely there may be a mild contact dermatitis at the site of application, where occasional pets experience crusting and hair loss. Even less common are idiosyncratic digestive or neurologic upset in very sensitive patients. Any pet with a chronic health condition or prior sensitivity to chemicals or vaccination should have a thorough veterinary exam and evaluation before applying any topical or oral pesticide product. I also recommend that the application of products such as Flea 5x be done on a different day(preferably at least 7 days apart) from other parasite control products such as heartworm prevention or immune challenges such as vaccination. Occasionally clients may see more fleas on their pets after immediately applying Flea 5x plus, but this is just the dying off of the flea population, as they rise to the top of the coat. Because of the often presence of eggs in the environment before the application of this product, it may take a few months to kill the total population of fleas in the home, which is why I often suggest treating the home as well when starting pets on a product like flea 5x plus. While flea 5x does not repel fleas and ticks, I have not found any current products on the market effective with that in my experience and opinion. I give this product an overall rating of 4.5(on scale of 1-5) with the efficacy and ease of use of a 5.

As most exterminators will tell you, the battle with external parasites and pests is an always evolving battle, as over time, parasites will develop partial resistance to products that had once worked almost perfectly in the past. This has been my experience with some of the older flea/tick formulations and has been reported by my veterinary colleagues and clients alike on occasion. While the older products are mostly still effective, companies are always researching new formulations to stay one step ahead of the development of resistance in the parasites. One of the latest formulations, Frontline Gold takes advantage of newer technologies and now has added an additional insect growth regulator, Pyriproxyfen, to its original formulation, to help enhance the efficacy of the Frontline plus product. The Frontline product is thus able to kill the next generation of flea larvae and eggs even more effectively by breaking the life cycle of the flea. The likelihood of flea immune resistance to this new triple action formula is thus significantly reduced. Given the increasing global warming seen in recent years, the expanding and increasing flea populations in heavily infested areas, however, do require a truly holistic approach by the animal guardian in treating the home, environment and yard for optimal flea control, as it is important to keep in mind that much of the flea life cycle still occurs in the home. While many clients find the more easily applied, self-puncturing tube dispensing method(often only requiring the use of one hand) to the old product, other clients find it difficult to see if all of the product has been dispensed from the colored tube. This new product, however, is quite effective, with only rare topical irritation at the site of the application an only rare complication. With that being said, I give this product an overall rating of a 5, with an ease of application of 4.

I love the broad acting antiparasitic effects of this product, which covers protection against a wider variety of pests to our pets than the competition. I feel it works the quickest in terms of flea/tick killing, and I love the fact that it repels fleas and ticks as well. Given that we are uncovering new and emerging tick born diseases, I prefer a product that repels in addition to quickly killing ticks, as well, and thus prevents tick attachment and transmission of disease. We are also now recognizing that mosquitoes can transmit diseases like West Nile virus to dogs, and so the added protective benefit of Advantix on mosquitoes and flies makes it quite attractive, especially for those clients whose pets spend a lot of time outside in the yard in the warmer months, when flies are most active. With this product I see much less fly strike and maggot infestation of outside dogs because of this added benefit. By repelling mosquitoes, we also get less transmission of potential heartworms to dogs. I have found that some smaller breeds of dogs are sometimes sensitive to the permethrin ingredient in this product, occasionally becoming excessively sensitive after application. I also find that although the product is labelled as water proof, on those pets, who are frequently bathed or swimming for long periods, that the product may need to be applied more frequently than once monthly. Some clients also find it somewhat more inconvenient in larger breeds having to apply the product in several spots, rather than in a single spot like its competitor.

Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors. The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.