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| Kills Fleas |
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| Repels Fleas |
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| Kills Flea eggs and Larvae | N/A | Prevents development | N/A |
| Kills Ticks |
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| Repels Ticks |
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| Kills and/or Repels Mosquitoes |
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| Prevents Heartworm |
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| Other Parasites Information | N/A | Controls ear mites, roundworms and hookworms. | Protects against 5 types of ticks, roundworms, and hookworms |
| Waterproof (shampooing once a week can reduce effectiveness) | N/A |
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N/A |
| Safe for pregnant or nursing Pets | The safe use of Credelio in breeding, pregnant or lactating dogs hasn't been evaluated. |
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The safe use of Simparica TRIO has not been evaluated in breeding, pregnant, or lactating dogs. |
| How long does it take to work | Credelio starts killing fleas within 4 hours of administration and kills over 99% of fleas within 8 hours of administration. | See a greater than 90% control of your flea infestation during the first month but because adult fleas will emerge from cocoons in your environment, you may see a few fleas for several months until the flea population is destroyed. | It starts to kill deer ticks within 8 hours, and fleas within 4 hours |
| Taste | Beef-flavored chewable | Applied to Skin | liver-flavored chewable tablet |
| Active Ingredient(s) | Lotilaner | Selamectin | Sarolaner, moxidectin, and pyrantel |
| RX Required |
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| Dosage | Monthly | ||
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| Video | Coming soon | Coming soon | Coming soon |
| Vet Review | Belonging to the latest generation of flea/tick parasiticides(known as Isoxazoline medications), these palatable, beef flavored chewable tablets kills fleas quite effective, with most adult fleas being killed within 8 hours. One of the downsides, as compared with Vectra 3D is that Credilio does not repel either fleas or ticks, and has no effect on biting mosquitoes, which are the main vectors that transmit heartworms to dogs. Credilio and products of its class are one of the most effective products against several species of severe disease transmitting ticks, including ones that transmit Lyme Disease, Ehrlichiosis, Rocky Mountain Spotted Fever and Anaplasmosis, which have been increasing in incidence in recent years. As with other members of this drug class, we have also used this drug in treatment and prevention of both demedex mites and scabies mites, although this is an off label use. Giving with a full meal reduces risks of digestive reaction. Overall the tablet is well tolorated, but occasional diarrhea, vomiting or digestive upset is seen. I would look to one of the other products like Vectra 3D, if there is a history of significant neurologic disease or seizures. I give this product an overall rating of a 4 out of 5. | This versatile topical product has the widest range of protection of both internal and external parasites. In both cats and dogs, all 3 stages of the flea life cycle are effectively controlled,in addition to ear mites. For dogs, there is also the wonderful treatment benefit of killing hidden scabies mites on the skin, which are so difficult for veterinarians to find on routine skin scrapings at our offices. In fact, when either I or veterinary dermatologists are presented with a very itchy dog, in addition to our allergy workups, we will often treat with this topical every few weeks to treat and rule out any hidden scabies mites contributing to the pet's itching. It is amazing how many dogs will respond to this treatment, leading me to believe that scabies mites are involved with a lot more itching problems in dogs than I first learned about in vet school. With the increased recognition and understanding of feline heartworm disease, this is often the first heartworm preventative that I will reach for in cats, especially given all of the other benefits above. While it is often effective for canine heartworm prevention as well, I have heard of rare lapses in protection, so I usually combine this topical in dogs with one of the oral heartworm prevention medications like Heartgard or Interceptor. The only disadvantage I have seen is the rare reaction on cats of mild digestive upset and temporary hair loss at the site of application. It also has the wonderful benefits of being water proof in only 2 hours after application, and in being approved for use in puppies as young as 6 weeks of age. | Coming soon |
Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors.
The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
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