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| Reduces Pain and Inflammation associated with Arthritis? |
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| Reduces Fever? |
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| Reduces Joint Stiffness? |
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| Controls Symptoms of Osteoarthritis |
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| Additional Benefits | Can also reduce pain associated with surgery or dental procedures | Also relieves pain and inflammation from hip dysplasia | Remedies swelling and itchy skin caused by allergies |
| What Makes it Different? | Blocks COX-2 enzymes trigger inflammation and contribute to pain in arthritic joints | Generic equivalent to Rimadyl, comes in chewable tablet or caplet form | Also treats inflammation due to Addison's disease |
| Recommended For? | Dogs | Dogs (Over 6 weeks of age) | Dogs & Cats |
| Product Type | Chewable Tablet | Chewable Tablet | Tablet |
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| RX Required |
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| How Long does it Take to Work? | Within Hours of Dose | Within Hours of Dose | - |
| Video | |||
| Ingredients | Deracoxib | Carprofen | Prednisone |
| Does it have long-term side effects? | Danger of serious damage to healthy by prolonged exposure if swallowed. May possibly affect kidneys, gastrointestinal tract, development and/or reproduction | Laboratory studies in anesthetized dogs and clinical field studies have demonstrated that carprofen is well tolerated in dogs after oral administration. | Prolonged use of corticosteroids may product posterior sub-capsular cataracts, glaucoma with possible damage to the optic nerves and may enhance the establishment of secondary ocular infections due to fungi or viruses. |
| Cautions | Do not use with aspirin, another NSAID such as etodolac, carprofen, or piroxicam, an over-the-counter cough, cold, allergy, or pain medication, warfarin, furosemide, an ACE inhibitor such as enalapril, a steroid such as prednisone, insulin, or probenecid. | Contact the veterinarian if the pet has bloody, black or tarry stools, blood in vomit, or swelling or rapid weight gain due to fluid retention. Do not use on cats. | Without first talking to your veterinarian, do not give your pet any over-the-counter or other prescription medications while giving prednisone. There are possible side effects, including insomnia, nausea, vomiting, upset stomach, and fatigue. |
| What are Customers saying Pros | Betty is an 8 year old Rotty with the typical old Rotty joint and movement issues. Deramaxx makes such a difference in her pain management and happiness level. She is able to jump and bound like a 5 year old Rotty again. Deramaxx will be with us until the end. | My poor old Lady and I share problems getting up and down ... the Novox has really helped her. Wish I could take some! (Just kidding, of course.) It really has made a difference in her mobility - and her disposition. Thanks! | ..nice to know I've got my good boy back for now. Great product!! |
| What are Customers saying Cons | ...his liver values came up and now his kidneys are in failure. | ...will not take Novox...I don't know if it has a bitter taste..."...may cause kidney failure. | - |
| Vet Recommendations | This close relative of the human arthritic drug celebrex, which has helped so many suffering human arthritis patients, has really shined in its veterinary use. All nonsteroidal anti inflammatory drugs on the market to varying degrees block enzymes in our pets bodies involved with pain and inflammation. The deramaxx difference and advantage is that unlike many competitor products, deramaxx does NOT block enzymes that are involved in blood clotting, protection of the stomach lining and kidney function, thus providing an increased balance of safety and efficacy over other products I have seen in practice. Deramaxx specifically targets the source of osteoarthritis inflammation and pain with ONE chewable tablet controlling inflammation for a full 24 hours. This FDA approved drug has been prescribed to over one million dogs over the past 2 years. One study with one of its major competitors, showed that lame dogs put more weight on the leg quicker and for longer periods than another drug of its class commonly prescribed. As with any individual drug of the nonsteroidal anti inflammatory class, there can be very rare reactions involving the digestive tract, kidneys or liver. I find that when we do complete blood and urine workups on pets before starting on this medication, that we are able to prescribe drugs like this more safely. For those pets who need deramaxx long term, blood work should be done every 4-6 months in my opinion. I often find that when using the wonderful neutraceuticals from 1800petmeds for arthritis like super joint enhancer, proanthozone, and super joint omega that I am able to use much lower doses of deramaxx in controlling chronic degenerative joint disease and arthritis in many of our aging dogs,, even only a dose or two a week in some cases, once the neutraceuticals take effect over several weeks. For some of the major orthopedic procedures done on dogs today, including fracture repair, joint reconstruction, and the ever increasing number of cruciate surgeries being done on dogs, that deramaxx offers superior relief and quicker return to function than some of the other competitor products. The main disadvantages I have found is the lack of an approved injectable medication for same day use in my surgery cases, as well as the lack of FDA labelled safety and approval for use in young puppies.6 weeks of age. Also it is so important for clients to review with their veterinarians any prior drug or antibiotic reactions, ot the use of any other over the counter drugs, other prescription medicines, as well as nutritional supplements that could interact with drugs of this class and potentially lead to increased complications. These issues should always be discussed with your vet on case by case basis, but by no means should discourage the use of this wonderful often life saving drug... | Currently under review | There is not a more widely used as well as widely misunderstood drug used in veterinary medicine than the use of oral prednisone. Since many of the chronic diseases treated in small animal veterinary medicine are often due to an overactive immune system response, whether talking about skin/ear allergies, chronic digestive tract inflammation, chronic respiratory or coughing issues, and even inflammation of the brain and spine, this drug is often prescribed by many veterinarians for these various conditions. It is important for animal guardians to understand that when using a drug like prednisone, we are often treating symptomatically, where we dont know or understand the cause of the chronic problems of these various organ systems in most cases. . In other words we are often quickly bandaiding the symptoms but not often addressing the underlying causes of the problems that often elude even the most intense diagnostic search. . . Except for what are called autoimmune diseases, where the body literally attacks its own tissues, such as the red blood cells or platelets, leading to life threatening blood disorders, or the joints in diseases like lupus or rheumatoid arthritis, the use of prednisone can often be curative in those conditions as the immune system is so overactive that the life of the animal can be at risk. However it is important for veterinarians to always look for underlying causes of any of these various disorders, so that cure is more likely, and to avoid the occasional side effects seen when this drug is used long term. When prednisone is overused topically and/or orally, side effects can include excessive thirst/urination/appetite, and panting, as well as a thinning of the skin, and weakening of the bones and ligaments of the body, in addition to predisposing to secondary infections particularly of the urinary tract, as well as in occasional cases of diabetes. If used in high doses or for long periods, digestive tract ulceration and bleeding can also occur. However if prednisone is used in appropriate fashions for the above chronic conditions, where the oral dose is tapered to the lowest effective dose to control clinical signs, hopefully every other or every third day in those chronic incurable conditions, than many dogs can remain on this drug long term. The most important point to understand, however, is that when on this drug long term, periodic blood and urine testing should be monitored to detect any early side effects. And while I try and use other milder drugs and various supplements or antihistamines listed on the 1800petmeds website , in some very severe skin allergies with incessant itching, sometimes low dose Prednisone is the only drug that can truly get the itch under control for symptomatic relief for the animals at a reasonable cost, without resorting to very expensive drugs like Atopica or trips to veterinary dermatologists which can cost hundreds to even thousands of dollars long term. I certainly prefer low dose infrequent dosing of Prednisone to control chronic clinical signs over the long acting cortisone injections that many vets use, which indeed have more significant side effects and risks outlined above. While taking everything above into account, and with adequate monitoring, I give Prednisone an overall rating of a 5 with an ease of use of a 5 as well. |
Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors.
The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
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