Galliprant vs. Metacam Comparison

Galliprant

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Metacam

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Quellin Carprofen Soft Chew - Generic to Rimadyl

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Reduces Pain and Inflammation associated with Arthritis?

Reduces Fever?

Reduces Joint Stiffness?

Controls Symptoms of Osteoarthritis

Additional Benefits

Targets canine osteoarthritis pain and inflammation while reducing the impact on GI, kidney, and liver homeostasis.

Oral suspension comes with graduated syringe for accuracy

Also relieves pain and inflammation from hip dysplasia

What Makes it Different?

Galliprant (grapiprant tablets) is a first-in-class non-COX-inhibiting prostaglandin receptor antagonist. It specifically blocks the EP4 receptor, the primary mediator of canine osteoarthritis pain and inflammation. Galliprant (grapiprant tablets) does not inhibit the production of many housekeeping prostanoids that maintain homeostatic functions.

Comes in an oral suspension for easy administration

Generic equivalent to Rimadyl, only comes in soft chewable

Recommended For?

Dogs (9 months of age or older, weighing 8 lbs or more)

Dogs (Over 6 months of age)

Dogs (Over six weeks of age)

Product Type

Tablet

Oral Suspension

Chewable Tablet

Usage

Quellin Carprofen Soft Chew - Generic to Rimadyl Usage

RX Required

How Long does it Take to Work?

Within Hours of Dose

Video

Ingredients

Grapiprant

Meloxicam

Carprofen

Does it have long-term side effects?

In a 9-month toxicity study, vomiting and soft-formed or mucus stool were observed in all groups, including controls, with higher incidence in grapiprant-treated dogs. Decreases in serum albumin and total protein were seen with increasing doses of grapiprant. Hypoalbuminemia and hypoproteinemia were reversible when treatement was discontinued. Three treated dogs and one control dog had elevated alkaline phosphatase values.

GI abnormalities (vomiting, soft stools, diarrhea, and inappetance) were the most common adverse reactions associated with the administration of meloxicam. In rare situations, death has been reported as an outcome of the adverse events listed above. Renal failure has been reported as an outcome of repeated oral dosing of cats.

Laboratory studies in anesthetized dogs and clinical field studies have demonstrated that Quellin is well tolerated in dogs after oral administration.

Cautions

Galliprant (grapiprant tablets) is for use in dogs 9 months of age or older, weighing 8 lbs or more only. Do not use in cats. Galliprant (grapiprant tablets) are not for use in humans. Keep this and all medications out of reach of children and pets. Consult a physician in case of accidental ingestion by humans. Store Galliprant (grapiprant tablets) out of reach of dogs and other pets in a secured location in order to prevent accidental ingestion or overdose.

Contact the veterinarian if the pet has bloody, black or tarry stools, blood in vomit, or swelling or rapid weight gain due to fluid retention. Do not us on cats.

Do Not Give To Cats

What are Customers saying Pros

I cannot say enough how great this med is. My lab’s pain was so bad that I thought she had experienced a stroke…..she couldn’t walk without help, and her face and eyes showed confusion and pain. After one pill, she began to feel better and in less than 24 hours she was back to her normal self. I was afraid I was going to lose her, but this med has brought her back to me. It is a miracle worker.

We moved and have a new vet who I asked if she had any ideas for improvement. Within two weeks of her being on Metacam, her whole life has changed. She, by her expression, feels SO much better, tries to bounce along -- still can't walk well -- and is barking and playing like she hasn't in five years!!!! We have a new dog!

These work VERY well for my girl. Her legs were very stiff and she couldn't hardly get up off the floor, but after just 2 days of these pills, she has that spunk back in her eye and moves around with no problems! She has even been jumping up on the bed again!! Love that these pills work so wonderfully!

What are Customers saying Cons

From a helping stand point it's perfect; he’s so much better…from a money standpoint, saddening this is so expensive.

...may cause kidney failure.

I ordered this generic version of Rimadyl chewables because of the price. However, these chewables do not taste the same (apparently) as the Rimadyl and my old girl won't touch them... even smothered in peanut butter, she won't go near them.

Vet Recommendations

There has been an exciting development in the area of pain management in the past year. The recognition, understanding, and use of pain management medications in veterinary medicine has grown dramatically, especially for osteoarthritis in dogs. Over the past 20 years, improved nonsteroidal anti-inflammatory medications such as Rimadyl, Metacam, Deramaxx, and Previcox, have indeed been great helps in managing pain and inflammation in arthritic patients, however, there remain risks in occasional, sensitive animals of serious side effects, whether it be on the digestive tract, kidneys or liver. With the arrival of the new drug Galliprant, conventional veterinarians now have a unique and innovative product that targets the clinical signs(i.e pain, inflammation) of arthritis by specifically blocking a particular receptor, while sparing other similar receptors to continue, do help with balance and health. Therefore there are much fewer risks of especially kidney and liver dysfunction. While GI side effects can occasionally occur, they are much rarer and milder than with many nonsteroidal anti-inflammatory medications and can be minimized by giving with food. The medication starts working within the day, but more typical is gradual improvement over the first month of therapy. While veterinarians are still gaining clinical experience in this newly approved drug, the main side effect rarely encountered is short lived vomiting, which typically resolves on its own. Even rarer are loose, mucoid stools. An outstanding benefit of this novel product is that it can be used in animals as young as one year of age. It also comes in a very palatable pork liver flavor formulation. I give this medication an overall rating of a 4.5.

Metacam is a very effective nonsteroidal anti inflammatory medication that has proven very effective in dogs. I have found it especially useful in very smaller dogs, where it is quite helpful in managing arthritis and pain, as well as helpful in reducing fevers as well. The only occasional side effects I have seen with this product is digestive upset, as well as even rare liver or kidney complications. I give this product an overall ranking of a 4.5 out of 5.

From the trustworthy and reliable drug company Bayer comes a brand new formulation (known as Quellin) of a time and tested non steroidal anti inflammatory drug carprofen and Rimadyl. For those dogs who are difficult to medicate or pill, this easy to use soft chewable is well accepted by most dogs, and avoid the use of pill pockets. They are also scored tablets, which allow for flexible dosing of dogs of all weights. This non steroidal anti inflammatory has many benefits in managing pain and inflammation, associated with surgery, as well as the inflammation associated with injuries and chronic arthritis. When given with food, this cuts down on the chance of digestive upset. In any pet undergoing chronic therapy with a drug like Quellin, blood work and urine analysis should be done to test for any pre existing medical conditions. This is an exciting new development with this chewable formulation of a very important anti inflammatory medication. I give it an overall rating of a 4.5 with an ease of use and efficacy/taste of a 5.

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