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Kills Fleas |
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Repels Fleas |
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Kills Flea eggs and Larvae |
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Breaks the flea cycle | Prevents Development |
Kills Ticks |
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Repels Ticks |
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Kills and/or Repels Mosquitoes |
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Prevents Heartworm |
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Other Parasites Information | Eliminates infestations with chewing lice, aids in the control of sarcoptic mange infestation |
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Controls adult hookworms and removes and controls adult roundworms & whipworms |
Waterproof (shampooing once a week can reduce effectiveness) |
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Not Applicable | N/A |
Safe for pregnant or nursing Pets |
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How long does it take to work | Kills Fleas within 12 hours and Ticks within 48 hours | Starts working immediately to stop the reproduction of adult fleas. | Begins to work Immediately, However, pre-existing flea populations may continue to develop and emerge. |
Taste | Applied to Skin | Unflavored liquid | Beef Flavor |
Active Ingredient(s) | Fipronil/(S)-Methoprene | Lufenuron | Milbemycin Oxime/Lufenuron |
RX Required |
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Dosage | Monthly | ||
Usage |
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Video | Coming soon | Coming soon | Coming soon |
Vet Review | I find that the effective combination of an ingredient like fipronil, along with the insect growth regulator methoprene, provides the best spectrum of activity and protection against all stages of the flea life cycle from egg through larval stage on to adult. Because of these two main ingredients and their method of action, I find that clients don't have to treat the environment as much. I find that this product tends to be safer in smaller breed animals when compared to its competition. I find its tick efficacy quite good. The fact that it is waterproof also allows clients, whose pets swim frequently, to confidently use this product during the swimming months. I also find that this product works the longest for fleas, while some of the competitive products have to be reapplied before the end of the month. The lack of label efficacy against mosquitoes and flies, as well as the fact that this product does not repel fleas or ticks are the two main disadvantages. As with any insecticidal products, I find that every pet is an individual, in terms of which of the products works best on them. When I am dealing with more of a flea issue in a patient, this is the product I will likely reach for first. | Because of the difficulty for some clients in getting their cats to take pills, the development of this flavorable suspension to mix easily with their wet food has made compliance and efficacy of flea control a lot easier. Getting felines to take medication can always be a challenge. When not accepted in food, many clients have found mixing in various tuna or clam juices, oil, broth, gravy or sardines another way of administering this and other medications. As mentioned in my product review on program tablets, this product works best when given with meals for maximal absorption as well as before fleas are firmly established on the pet and in the home. It works by preventing development of flea eggs and larvae by in essence sterilizing the adult fleas who happen to bite the animal. The product does not kill existing adult fleas and must be combined with other products like Capstar or topical Advantage or Frontline in pets with active flea populations. I find it works best as a preventative before flea season. Many clients will chose to use this and other flea products year round due to the warming of the climate and the unpredictability of the flea season. I give this product an overall rating of a 4 with an ease of use and taste a 5 and efficacy a 4. | Sentinel is a wonderful combination of the heartworm prevention pill interceptor and the flea control product program both in this one pill. Many clients enjoy the convenience of having such broad acting internal and external parasites in one pill, without having to worry about giving two separate medicines. Lufenuron, which is the main flea control ingredient, stops the flea life cycle in its track at the egg and larval stage, thus being like a birth control pill for fleas who get on our pets. Given that the main problem of fleas is how rapidly they reproduce, this pill literally stops escalating growth of flea populations, before they can become established in our homes, where most of the flea life cycle occurs. The main disadvantage to this product is that it does not kill or repel adult fleas, so in situations with already established heavy infestations, it is best combined with a great topical product like advantage or front line or with the oral adulticide flea pill Capstar for maximal effect. The only other rare disadvantage I see is the slight increase in reactions when two products are combined into one like this, but fortunately this is not common in clinical practice. With milbemycin for prevention of heartworms and controlling and treating most common intestinal worms, I overall highly recommend this versatile product. |