SAVE 50% ON NEXGARD W/AUTOSHIPUse code NEXGARD50 (Up to $50 max. Exclusions apply)
SAVE AN EXTRA $5 - $20 OFFUse code PETS in cart (Exclusions apply)
Kills Fleas |
![]() |
![]() |
![]() |
Repels Fleas |
![]() |
![]() |
![]() |
Kills Flea eggs and Larvae |
![]() |
![]() |
Prevents Development |
Kills Ticks |
![]() |
![]() |
![]() |
Repels Ticks |
![]() |
![]() |
![]() |
Kills and/or Repels Mosquitoes |
![]() |
![]() |
![]() |
Prevents Heartworm |
![]() |
![]() |
![]() |
Other Parasites Information | Kills chewing lice and controls mites that may cause sarcoptic mange. | Repels and prevents blood-feeding by biting flies and kills chewing lice. |
![]() |
Waterproof (shampooing once a week can reduce effectiveness) |
![]() |
![]() |
Not Applicable |
Safe for pregnant or nursing Pets |
![]() |
Consult your veterinarian |
![]() |
How long does it take to work | Kills fleas and ticks with the same efficacy as Frontline Top Spot. | Kills Fleas 12 hours | Begins to work immediately. |
Taste | Applied to Skin | Applied to Skin | Beef Flavor |
Active Ingredient(s) | Fipronil | Imidacloprid/ Permethrin/Pyriproxyfen | Lufenuron |
RX Required |
![]() |
![]() |
![]() |
Dosage | |||
Usage |
![]() |
![]() |
![]() |
Video | Coming soon | Coming soon | Coming soon |
Vet Review | I recently completed a small clinical trial using Flea 4X topical product for dogs in my veterinary clinic. And I must say that the initial reports on efficacy and safety has been excellent. With the main ingredient being the tried and tested fipronil, this product is very effective in controlling fleas, ticks, chewing lice and mosquitoes. It is also labelled to control mites that cause sarcoptic mange in dogs as well. This product is a wonderful generic alternative to the Frontline product that has been out for years. Clients have loved the economic savings of this product over similar topical flea and tick preventatives. It is manufactured exclusively in the United States, as well as having the trustworthy and reliable 1800petmeds label on the packaging. It is also water proof for those canine patients who spend a lot of time outside and/or swimming during the summer months. Clients are reporting back to me quick flea and tick killing that lasts up to several weeks in treated pets. I highly recommend this product to those canine guardians seeking out an effective and economic alternative to similar products on the market. | I love the broad acting antiparasitic effects of this product, which covers protection against a wider variety of pests to our pets than the competition. I feel it works the quickest in terms of flea/tick killing, and I love the fact that it repels fleas and ticks as well. Given that we are uncovering new and emerging tick born diseases, I prefer a product that repels in addition to quickly killing ticks, as well, and thus prevents tick attachment and transmission of disease. We are also now recognizing that mosquitoes can transmit diseases like West Nile virus to dogs, and so the added protective benefit of Advantix on mosquitoes and flies makes it quite attractive, especially for those clients whose pets spend a lot of time outside in the yard in the warmer months, when flies are most active. With this product I see much less fly strike and maggot infestation of outside dogs because of this added benefit. By repelling mosquitoes, we also get less transmission of potential heartworms to dogs. I have found that some smaller breeds of dogs are sometimes sensitive to the permethrin ingredient in this product, occasionally becoming excessively sensitive after application. I also find that although the product is labelled as water proof, on those pets, who are frequently bathed or swimming for long periods, that the product may need to be applied more frequently than once monthly. Some clients also find it somewhat more inconvenient in larger breeds having to apply the product in several spots, rather than in a single spot like its competitor. | For my clients who prefer an effective non-pesticide manner of preventing and controlling fleas on their dogs and cats, program offers a wonderful alternative. When this product first came out, I used to educate my clients on the fact that it was in essence a birth control pill for fleas. The main ingredient lufeneron is an insect growth regulator that does not kill adult fleas, but sterilizes adult fleas and prevents them from laying eggs that develop into larvae and future adults. Each adult flea can lay up to 2000 eggs in its life. It is because of this effect on flea development which makes program such a wonderful preventative. For existing flea infestations, I don't find this product works as well unless it is combined with oral Capstar, which kills adult fleas on cats and/or topical products like Frontline or Advantage. I have found this product both very safe and effective with only rare side effects seen i.e rare digestive upset. It is best given with a meal for maximal absorption which is hard on some kitty owners My overall rating of this product is a 4 with ease of use a 4, taste a 4 and efficacy a 5, in particular for preventing flea infestations before they become established. |