Advantage Multi vs. Seresto for Cats Comparison

Advantage Multi

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all weights, 15" collar length

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EasySpot for Cats

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Kills Fleas

Repels Fleas

Kills Flea eggs and Larvae

Prevents Development

Kills Ticks

Repels Ticks

Kills and/or Repels Mosquitoes

Prevents Heartworm

Other Parasites Information

Controls ear mites, hookworms and roundworms.

Chewing lice for up to 30 days.

Waterproof (shampooing once a week can reduce effectiveness)

Safe for pregnant or nursing Pets

Consult your veterinarian

How long does it take to work

Kills fleas within 12 hours.

Starts working in 1 hour

Taste

Applied To Skin

Applied to skin

Active Ingredient(s)

Imidacloprid/Moxidectin

Fipronil

RX Required

Dosage

Usage

Video

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Vet Review

By combining imidacloprid and moxidectin, Advantage Multi offers the wonderful benefit of broad protection against BOTH common internal and external parasites in dogs and cats. An important area of coverage includes not only adult stages, but the immature stages of roundworms and hookworms, two parasites that are a risk to people if not prevented in our pets. It also treats and controls, and prevents whipworms, which are difficult to eradicate in both dogs and the environment. When applied monthly, it is almost 100 percent effective in preventing heartworm disease in dogs and cats. Additional benefits of treating scabies and demodectic mange and ear mites make this a very attractive product. All of this with the wonderful flea control benefits of the product advantage. The greatest benefit I see with this versatile product is that it takes the labor out of administering a myriad of medications to dogs to control these varied internal and external parasites. I also find that it kills the larval stages of fleas in the home surroundings of treated pets, which is a wonderful added benefit. I have on rare occasions seen topical irritation and sensitivity at the site of application, and even more scarce neurological reactions in hypersensitive pets. The only other downside would be the potential high cost of this product, as well as the need for clients to obtain a prescription from their veterinarian. Overall, however, I have found this product to be an excellent and safe all around internal and external parasite control manager in our dogs and cats.

This reliable and more economical alternative to Frontline comes from a very reliable company, Elanco. Its main ingredient, fipronil, probably has the most clinical record of experience of efficacy over many years, in killing both adult fleas before they lay eggs, as well as various species of ticks. Its safety is touted by supposedly targeting only the nervous system of the pests. With cats, we always must be careful when evaluating the newer generation of emerging pesticides for fleas and ticks that are coming out, as kitties' detoxification pathways are typically more sensitive than dogs'. Most kitties tolerate this single spot application quite well. In addition to being waterproof, so important for outdoor kitties, this product is easier to apply than most competitors, as well as leaving no pungent or chemical smell like many over the counter competitor products. Most of my clients have found it as effective as Frontline, but not as quick as Advantage. Some clients have complained that it does not seem to repel the ticks, who can occasionally be found attached to the skin before they die. Not only it is important in using products like Easy Spot to prevent flea bite anemia in cats, and unsightly tapeworms, but in recent years, fleas have been shown to carry an increasing number of serious diseases and infections, including Bartonella species, amongst others. Another benefit of this product is that it is labeled as safe to use in pregnant or nursing cats. Side effects, although rare, may include topical irritation at the site of application, lethargy, as well as rare twitching reactions, agitation, and/or restlessness. These are typically short-lived, and fortunately, are very uncommon across pet populations that the product has been used. Some veterinarians and experts have wondered about the recent resistance of fleas to some of the fipronil-based products, but that has not been my experience. I give this product an overall rating of a 4, with an ease of application and efficacy of 4, as well.

Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors. The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.