Activyl vs. Bravecto for Cats Comparison

Activyl

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Bravecto for Cats

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Frontline Plus

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Kills Fleas

Repels Fleas

Kills Flea eggs and Larvae

Kills Ticks

Repels Ticks

Kills and/or Repels Mosquitoes

Prevents Heartworm

Other Parasites Information

Eliminates infestations with chewing lice, aids in the control of sarcoptic mange infestation

Waterproof (shampooing once a week can reduce effectiveness)

Safe for pregnant or nursing Pets

The safety of Bravecto has not been established in breeding, pregnant and lactating cats.

How long does it take to work

Reapply Activyl every 30 days.

Kills 100% of fleas within 8 hours of application.

Kills Fleas within 12 hours and Ticks within 48 hours

Taste

Applied to skin

Applied to Skin

Active Ingredient(s)

indoxacarb

Fluralaner

Fipronil/(S)-Methoprene

RX Required

Dosage

Monthly

Usage

Video

Coming soon

Vet Review

Another recently available new topical flea preventative for dogs and cats. This new product works by being activated by only the flea's enzyme systems into a flea specific mechanism which paralyzes and kills the adult flea. The company claims that it does not get into the blood stream, but stays only in the superficial skin layers of the pet. Any adult fleas which come into contact with this product are quickly killed so that fleas do not have to actually bite the pet, which is tremendously helpful in those flea-allergic pets, where it only takes a few flea bites to set off an extensive itchy allergic reaction. Another wonderful benefit of this product is that it is waterproof, which is especially helpful in those active outside pets who are exposed to rain or like to swim. This effective product starts working within 12 hours of application, where over 90% of adult fleas are killed. Another excellent benefit of this product is that it also inhibits the development of flea eggs and larvae in the environment, which is a big bonus since much of the flea life cycle occurs in the home environment. While Activyl is very safe and effective for most pets, I have seen occasional rare reactions in sensitive pets, which most commonly is seen as irritation or excessive itchiness at the site of application. While the company says that it is odorless, some of my clients have said that they do sense an odor within the first several days of application, as well as leaving an occasional oily film for the first day or two following application. This film, however usually quickly disappears. The only other very rare reactions include digestive upset and/or drooling/neurological reactions, and certainly if a pet has any chronic digestive weaknesses or history of seizures, etc then the local veterinarian should be consulted before applying the product. I give this product an overall rating of 4, with an ease of use of 4.

Flea control in cats is always challenging, not only in terms of safe products, but also in ease of application, and ultimately performance. Over the past several years the oral products like Bravecto and Nexguard have been highly effective for flea and tick control in dogs, as well as surprisingly other, unforeseen benefits such as treating, controlling and often curing previously frustrating Demodex mite infestations, and for much longer periods of time; 3 months of protection after one tablet. While the drug company has not come out with a similar oral formulation for cats, they have come out with a topical formulation, which also is labeled as effective for up to 3 months after one application. Obviously, handling one's kitty only once for a flea/tick treatment over 3 months is certainly welcome to most feline guardians. While I don't have lots of clinical experience with this product, reports from the field have found it highly effective in treated patients. As with many other products, it is also often important to treat the home environment, where 90 percent of the flea life cycle occurs. While the product is being reported as highly effective, I am concerned about using a product labeled for 3 months in cats after one use, especially if a sensitive feline patient suffers a reaction. Occasional reactions reported include transient irritation at the site of the product application, as well as occasional digestive and neurological reactions, which may be significant. While the product is highly effective for an extended period and easy to use, I would tend to reach for products that are shorter acting, although they will, of course, have to be applied or given more frequently.

I find that the effective combination of an ingredient like fipronil, along with the insect growth regulator methoprene, provides the best spectrum of activity and protection against all stages of the flea life cycle from egg through larval stage on to adult. Because of these two main ingredients and their method of action, I find that clients don't have to treat the environment as much. I find that this product tends to be safer in smaller breed animals when compared to its competition. I find its tick efficacy quite good. The fact that it is waterproof also allows clients, whose pets swim frequently, to confidently use this product during the swimming months. I also find that this product works the longest for fleas, while some of the competitive products have to be reapplied before the end of the month. The lack of label efficacy against mosquitoes and flies, as well as the fact that this product does not repel fleas or ticks are the two main disadvantages. As with any insecticidal products, I find that every pet is an individual, in terms of which of the products works best on them. When I am dealing with more of a flea issue in a patient, this is the product I will likely reach for first.

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