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Kills Fleas |
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Repels Fleas |
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Kills Flea eggs and Larvae | Prevents Development | Prevents Development | Prevents all flea stages (eggs, pupae, larvae, and adult fleas) from developing. |
Kills Ticks |
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Repels Ticks |
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Kills and/or Repels Mosquitoes |
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Prevents Heartworm |
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Other Parasites Information | Eliminates infestations with chewing lice, aids in the control of sarcoptic mange infestation | Controls adult hookworms and removes and controls adult roundworms & whipworms | Also kills biting and sand flies, live and mites for one month |
Waterproof (shampooing once a week can reduce effectiveness) |
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N/A |
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Safe for pregnant or nursing Pets |
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How long does it take to work | Works with the same efficacy as Frontline Top Spot | Begins to work Immediately, However, pre-existing flea populations may continue to develop and emerge. | Starts to reduce flea feeding in just 5 minutes |
Taste | Applied To Skin | Beef Flavor | Topical |
Active Ingredient(s) | Fipronil | Milbemycin Oxime/Lufenuron | Dinotefuran, Pyriproxyfen, Permethrin |
RX Required |
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Dosage | |||
Usage |
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Video | Coming soon | Coming soon | Coming soon |
Vet Review | Currently under review | Sentinel is a wonderful combination of the heartworm prevention pill interceptor and the flea control product program both in this one pill. Many clients enjoy the convenience of having such broad acting internal and external parasites in one pill, without having to worry about giving two separate medicines. Lufenuron, which is the main flea control ingredient, stops the flea life cycle in its track at the egg and larval stage, thus being like a birth control pill for fleas who get on our pets. Given that the main problem of fleas is how rapidly they reproduce, this pill literally stops escalating growth of flea populations, before they can become established in our homes, where most of the flea life cycle occurs. The main disadvantage to this product is that it does not kill or repel adult fleas, so in situations with already established heavy infestations, it is best combined with a great topical product like advantage or front line or with the oral adulticide flea pill Capstar for maximal effect. The only other rare disadvantage I see is the slight increase in reactions when two products are combined into one like this, but fortunately this is not common in clinical practice. With milbemycin for prevention of heartworms and controlling and treating most common intestinal worms, I overall highly recommend this versatile product. | For clients that prefer an outstanding topical medication that has thus far had an excellent record of efficacy against both fleas and ticks. This product includes 3 very powerful and synergistic flea/tick pesticides that work in slightly different ways, with one preventing development of flea eggs and larvae, while another ingredient quickly kills; killing probably the fastest of any products on the market, starting to act within 5 minutes. Ticks will take somewhat longer, but within 2 days most ticks are killed. The addition of the permethrin ingredient does add the benefit of this product in BOTH repelling and killing ticks, , as well as the additional benefit of killing and repelling mosquitoes, the main vectors of heartworm disease in dogs and cats. As with other topicals, occasionally pets will develop an irritation or sensitivity at the sight of application, with some pets being occasionally restless, agitated, or fidgety. On rare occasions vomiting and/or diarrhea may be seen but this has not been much of a problem in clinical practice, where most pets seem to tolerate the product quite well. While the trio of main ingredients in this product seem to provide additional efficacy and coverage of various stages of the external parasites, including the benefit of repelling them, I am always a bit cautious about combination products like this, which rarely may lead to unknown chronic side effects that we are not yet aware of. With that consideration, this product is still an excellent and effective choice. I give this product an overall rating of 4 out of 5. |