1800PetMeds

Activyl Tick Plus

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Fiproguard - Generic To Frontline Top Spot

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Flea4X for Dogs

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Kills Fleas

Repels Fleas

Kills Flea eggs and Larvae

Kills Ticks

Repels Ticks

Kills and/or Repels Mosquitoes

Prevents Heartworm

Other Parasites Information

Controls and kills chewing lice

Kills chewing lice and controls mites that may cause sarcoptic mange.

Waterproof (shampooing once a week can reduce effectiveness)

Safe for pregnant or nursing Pets

How long does it take to work

Reapply every 30 days.

Works with the same efficacy as Frontline Top Spot

Kills fleas and ticks with the same efficacy as Frontline Top Spot.

Taste

Applied to skin

Applied to Skin

Active Ingredient(s)

Indoxacarb, Permethrin

Fipronil

RX Required

Dosage

Usage

Video

Coming soon

Vet Review

When the Activyl product line came out several years ago, it was touted as a totally novel new product on the market that would not have the problems of emerging flea resistance to products that has believed to been increasing in recent years with the old standby products in some cases. It supposedly works through a unique process of bioactivation using only the flea enzymes in activating the main ingredient, indoxacarb, in killing fleas. Along with the permethrin ingredient for tick coverage and control, it would seem like this would be a first line or excellent choice for those looking for a novel and comprehensive flea/tick product for their dogs. And while it is also effective in preventing flea eggs and larvae from developing as well, and can be highly effective in today's war against fleas and ticks, I have seen occasional problems with this product, as reported by clients. While its deeper penetration in the fatty oils of the skin may be a benefit, and while the product is not reported to be absorbed systemically, I have seen occasional and severe side effects reported by animal guardians. As with most other topical products in this venue, this particular product can occasionally cause irritation and itching at the site of application, which while usually only transient for a day or two, in some pets the itching and allergic reaction has been noted to intensify, necessitating anti-itch medications for relief. Some clients have also reported an odd odor from the application site for a while, as well as an oily film, which may persist for a few days. While many clients do report this product highly effective when other competitor products may have failed them recently, these occasional reactions are important to note, especially in a very sensitive or geriatric animal, and/or one with a chronic medical condition. On very rare occasions, clients have reported digestive side effects, as well as rare neurological weakness, stiffness or even spasms. While the vast majority of clients are satisfied with this product's performance and reliability, the decision on using this stronger, newer way of flea and tick control, should be made after careful consideration of patient history, as well as discussion with the local veterinarian. I give this product an overall rating of a 4, with an ease of use of a 5, with a mid-rating safety level of 3.

FiproGuard is a generic equivalent to Frontline Top Spot. Fiproguard is not manufactured by the makers of Frontline Top Spot, but is EPA-approved for the sale in the USA. It is new to the market and not yet rated.

I recently completed a small clinical trial using Flea 4X topical product for dogs in my veterinary clinic. And I must say that the initial reports on efficacy and safety has been excellent. With the main ingredient being the tried and tested fipronil, this product is very effective in controlling fleas, ticks, chewing lice and mosquitoes. It is also labelled to control mites that cause sarcoptic mange in dogs as well. This product is a wonderful generic alternative to the Frontline product that has been out for years. Clients have loved the economic savings of this product over similar topical flea and tick preventatives. It is manufactured exclusively in the United States, as well as having the trustworthy and reliable 1800petmeds label on the packaging. It is also water proof for those canine patients who spend a lot of time outside and/or swimming during the summer months. Clients are reporting back to me quick flea and tick killing that lasts up to several weeks in treated pets. I highly recommend this product to those canine guardians seeking out an effective and economic alternative to similar products on the market.

Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors. The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.