Frontline Plus vs. Frontline Top Spot Comparison

Frontline Plus

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Frontline Top Spot

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Sentinel Flavor Tabs

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Kills Fleas

Repels Fleas

Kills Flea eggs and Larvae

Prevents Development

Kills Ticks

Repels Ticks

Kills and/or Repels Mosquitoes

Prevents Heartworm

Other Parasites Information

Eliminates infestations with chewing lice, aids in the control of sarcoptic mange infestation

Kills chewing lice in dog and puppies and controls mites that may cause sarcoptic mange.

Controls adult hookworms and removes and controls adult roundworms & whipworms

Waterproof (shampooing once a week can reduce effectiveness)

N/A

Safe for pregnant or nursing Pets

How long does it take to work

Kills Fleas within 12 hours and Ticks within 48 hours

Kills Fleas within 12 hours of contact and Ticks within 48 hours of contact.

Begins to work Immediately, However, pre-existing flea populations may continue to develop and emerge.

Taste

Applied to Skin

Applied To Skin

Beef Flavor

Active Ingredient(s)

Fipronil/(S)-Methoprene

Fipronil

Milbemycin Oxime/Lufenuron

RX Required

Dosage

Monthly

Usage

Video

Coming soon

Vet Review

I find that the effective combination of an ingredient like fipronil, along with the insect growth regulator methoprene, provides the best spectrum of activity and protection against all stages of the flea life cycle from egg through larval stage on to adult. Because of these two main ingredients and their method of action, I find that clients don't have to treat the environment as much. I find that this product tends to be safer in smaller breed animals when compared to its competition. I find its tick efficacy quite good. The fact that it is waterproof also allows clients, whose pets swim frequently, to confidently use this product during the swimming months. I also find that this product works the longest for fleas, while some of the competitive products have to be reapplied before the end of the month. The lack of label efficacy against mosquitoes and flies, as well as the fact that this product does not repel fleas or ticks are the two main disadvantages. As with any insecticidal products, I find that every pet is an individual, in terms of which of the products works best on them. When I am dealing with more of a flea issue in a patient, this is the product I will likely reach for first.

One of my favorite and most widely prescribed flea and tick control products in practice front line top spot offers not only the ease of application in one spot, where it collects in the hair follicles and skin oils and gradually released over the month, but also a wide area of safety in most pets, including breeding, pregnant and lactating dogs. . It will kill adult fleas and larvae by selectively affecting the parasite's nervous system. Efficacy against flea eggs is variable in my experience and opinion. It will also kill chewing lice and some veterinarians, including myself have seen it work to help control demodectic mange and ear mites, although it is it not approved for use for these uses. This versatile product will also kill all stages of various ticks including brown dog ticks, american dog ticks, lone star ticks and deer ticks. I have also used it to control sarcoptic mange infestations in dogs, but will often go to topical revolution first in sarcoptic mange or ivermectin as my first choices for scabies. In general I find that fleas and ticks are generally killed before they have the chance to transmit diseases in patients, usually being close to 100% effective within 24 to 48 hours. The formulation is water proof so it is certainly appropriate to use in those outdoor dogs who love to swim. I have only seen occasional/rare side effects at the sight of application, and even more rare systemic reactions like digestive upset or neurological reactions or blood disorders in extremely sensitive pets. However these reactions are rare in my experience. In geriatric patients or sick patients or those with chronic disease it is important to consult with your veterinarian before applying this or any other topical flea and tick product.

Sentinel is a wonderful combination of the heartworm prevention pill interceptor and the flea control product program both in this one pill. Many clients enjoy the convenience of having such broad acting internal and external parasites in one pill, without having to worry about giving two separate medicines. Lufenuron, which is the main flea control ingredient, stops the flea life cycle in its track at the egg and larval stage, thus being like a birth control pill for fleas who get on our pets. Given that the main problem of fleas is how rapidly they reproduce, this pill literally stops escalating growth of flea populations, before they can become established in our homes, where most of the flea life cycle occurs. The main disadvantage to this product is that it does not kill or repel adult fleas, so in situations with already established heavy infestations, it is best combined with a great topical product like advantage or front line or with the oral adulticide flea pill Capstar for maximal effect. The only other rare disadvantage I see is the slight increase in reactions when two products are combined into one like this, but fortunately this is not common in clinical practice. With milbemycin for prevention of heartworms and controlling and treating most common intestinal worms, I overall highly recommend this versatile product.

Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors. The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.