Credelio Chewable Tablets for Dogs vs. Sentinel Spectrum Chews Comparison

Credelio Chewable Tablets for Dogs

Learn More

Sentinel Spectrum Chews

Learn More

Vectra 3D

Learn More

Kills Fleas

Repels Fleas

Kills Flea eggs and Larvae

N/A

Prevents Development

Prevents all flea stages (eggs, pupae, larvae, and adult fleas) from developing.

Kills Ticks

Repels Ticks

Kills and/or Repels Mosquitoes

Prevents Heartworm

Other Parasites Information

N/A

Protects against heartworms, fleas, roundworms, hookworms, whipworms and tapeworms.

Also kills biting and sand flies, live and mites for one month

Waterproof (shampooing once a week can reduce effectiveness)

N/A

Safe for pregnant or nursing Pets

The safe use of Credelio in breeding, pregnant or lactating dogs hasn't been evaluated.

The safety of Sentinel Spectrum has not been evaluated in dogs used for breeding or in lactating females.

How long does it take to work

Credelio starts killing fleas within 4 hours of administration and kills over 99% of fleas within 8 hours of administration.

Begins to work Immediately,

Starts to reduce flea feeding in just 5 minutes

Taste

Beef-flavored chewable

Topical

Active Ingredient(s)

Lotilaner

Milbemycin oxime, lufenuron, and praziquantel.

Dinotefuran, Pyriproxyfen, Permethrin

RX Required

Dosage

Usage

Video

Coming soon

Vet Review

Belonging to the latest generation of flea/tick parasiticides(known as Isoxazoline medications), these palatable, beef flavored chewable tablets kills fleas quite effective, with most adult fleas being killed within 8 hours. One of the downsides, as compared with Vectra 3D is that Credilio does not repel either fleas or ticks, and has no effect on biting mosquitoes, which are the main vectors that transmit heartworms to dogs. Credilio and products of its class are one of the most effective products against several species of severe disease transmitting ticks, including ones that transmit Lyme Disease, Ehrlichiosis, Rocky Mountain Spotted Fever and Anaplasmosis, which have been increasing in incidence in recent years. As with other members of this drug class, we have also used this drug in treatment and prevention of both demedex mites and scabies mites, although this is an off label use. Giving with a full meal reduces risks of digestive reaction. Overall the tablet is well tolorated, but occasional diarrhea, vomiting or digestive upset is seen. I would look to one of the other products like Vectra 3D, if there is a history of significant neurologic disease or seizures. I give this product an overall rating of a 4 out of 5.

There is an outstanding new comprehensive internal and external parasite control product called sentinel spectrum, which combines 3 excellent worming medications that treat and prevent a wide variety of parasites from heartworms, intestinal worms ranging from tapeworms to whipworms, as well as controlling flea infestations. That is 6 types of parasites controlled with one pill. That is a wonderful benefit of this product, along with the tastiest beef flavored tablet. The only down side to this product in my experience and opinion is that it does not kill or repel fleas, but breaks the flea life cycle by preventing adult fleas from laying eggs, as well as killing the eggs. Adult fleas still may bite your dog, which may cause allergic dermatitis in some sensitive animals. I have also seen occasional pet vomit on this product, which is usually avoided by giving with a meal. A wonderful benefit over topical parasite control measures is that by combining all of the wonderful ingredients into a pill formulation prevents exposure of the humans in the household to chemical pesticide residues. I give this product an overall rating of a 4, with a taste of 4 and ease of use of a 5.

For clients that prefer an outstanding topical medication that has thus far had an excellent record of efficacy against both fleas and ticks. This product includes 3 very powerful and synergistic flea/tick pesticides that work in slightly different ways, with one preventing development of flea eggs and larvae, while another ingredient quickly kills; killing probably the fastest of any products on the market, starting to act within 5 minutes. Ticks will take somewhat longer, but within 2 days most ticks are killed. The addition of the permethrin ingredient does add the benefit of this product in BOTH repelling and killing ticks, , as well as the additional benefit of killing and repelling mosquitoes, the main vectors of heartworm disease in dogs and cats. As with other topicals, occasionally pets will develop an irritation or sensitivity at the sight of application, with some pets being occasionally restless, agitated, or fidgety. On rare occasions vomiting and/or diarrhea may be seen but this has not been much of a problem in clinical practice, where most pets seem to tolerate the product quite well. While the trio of main ingredients in this product seem to provide additional efficacy and coverage of various stages of the external parasites, including the benefit of repelling them, I am always a bit cautious about combination products like this, which rarely may lead to unknown chronic side effects that we are not yet aware of. With that consideration, this product is still an excellent and effective choice. I give this product an overall rating of 4 out of 5.

Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors. The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.