Advantage II vs. Frontline Gold Comparison

Advantage II

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Frontline Gold

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K9 Advantix II

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Kills Fleas

Repels Fleas

Kills Flea eggs and Larvae

Kills Ticks

Repels Ticks

Kills and/or Repels Mosquitoes

Prevents Heartworm

Other Parasites Information

Treats, Prevents, and Controls Lice Infestations

Eliminates infestations with chewing lice

Repels and prevents blood-feeding by biting flies and kills chewing lice.

Waterproof (shampooing once a week can reduce effectiveness)

Safe for pregnant or nursing Pets

Consult your veterinarian

Consult your veterinarian

How long does it take to work

Kills fleas in 12 hours

Starts killing fleas in 30 minutes

Kills Fleas 12 hours

Taste

Applied to Skin

Applied to skin

Applied to Skin

Active Ingredient(s)

Imidacloprid/Pyriproxyfen

Fipronil, S-methoprene, Pyriproxyfen

Imidacloprid/ Permethrin/Pyriproxyfen

RX Required

Dosage

Usage

Video

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Vet Review

The non-greasy, non-odor formulation is a definite plus when used on sensitive patients, especially cats.I find that advantage kills fleas and larvae more quickly than some of the other products out there, often resulting in quicker relief of flea allergy dermatitis symptoms in dogs and cats. Overall I have found it quite safe and have seen the fewest topical or rare systemic reactions in my practice over the years. The main disadvantage I have found is that in heavy flea infestations that the efficacy may wear off in less than one month, necessitating some vets to recommend more frequent off label use of this product every few weeks. It also does not control ticks as well on dogs and cats. I find that advantage works most effectively when combined with good environmental flea control at home.

As most exterminators will tell you, the battle with external parasites and pests is an always evolving battle, as over time, parasites will develop partial resistance to products that had once worked almost perfectly in the past. This has been my experience with some of the older flea/tick formulations and has been reported by my veterinary colleagues and clients alike on occasion. While the older products are mostly still effective, companies are always researching new formulations to stay one step ahead of the development of resistance in the parasites. One of the latest formulations, Frontline Gold takes advantage of newer technologies and now has added an additional insect growth regulator, Pyriproxyfen, to its original formulation, to help enhance the efficacy of the Frontline plus product. The Frontline product is thus able to kill the next generation of flea larvae and eggs even more effectively by breaking the life cycle of the flea. The likelihood of flea immune resistance to this new triple action formula is thus significantly reduced. Given the increasing global warming seen in recent years, the expanding and increasing flea populations in heavily infested areas, however, do require a truly holistic approach by the animal guardian in treating the home, environment and yard for optimal flea control, as it is important to keep in mind that much of the flea life cycle still occurs in the home. While many clients find the more easily applied, self-puncturing tube dispensing method(often only requiring the use of one hand) to the old product, other clients find it difficult to see if all of the product has been dispensed from the colored tube. This new product, however, is quite effective, with only rare topical irritation at the site of the application an only rare complication. With that being said, I give this product an overall rating of a 5, with an ease of application of 4.

I love the broad acting antiparasitic effects of this product, which covers protection against a wider variety of pests to our pets than the competition. I feel it works the quickest in terms of flea/tick killing, and I love the fact that it repels fleas and ticks as well. Given that we are uncovering new and emerging tick born diseases, I prefer a product that repels in addition to quickly killing ticks, as well, and thus prevents tick attachment and transmission of disease. We are also now recognizing that mosquitoes can transmit diseases like West Nile virus to dogs, and so the added protective benefit of Advantix on mosquitoes and flies makes it quite attractive, especially for those clients whose pets spend a lot of time outside in the yard in the warmer months, when flies are most active. With this product I see much less fly strike and maggot infestation of outside dogs because of this added benefit. By repelling mosquitoes, we also get less transmission of potential heartworms to dogs. I have found that some smaller breeds of dogs are sometimes sensitive to the permethrin ingredient in this product, occasionally becoming excessively sensitive after application. I also find that although the product is labelled as water proof, on those pets, who are frequently bathed or swimming for long periods, that the product may need to be applied more frequently than once monthly. Some clients also find it somewhat more inconvenient in larger breeds having to apply the product in several spots, rather than in a single spot like its competitor.

Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors. The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.