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Kills Fleas |
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Repels Fleas |
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Kills Flea eggs and Larvae |
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N/A |
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Kills Ticks |
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Repels Ticks |
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Kills and/or Repels Mosquitoes |
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Prevents Heartworm |
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Other Parasites Information | NA | N/A |
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Waterproof (shampooing once a week can reduce effectiveness) |
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N/A | N/A |
Safe for pregnant or nursing Pets | The safety of Bravecto has not been established in breeding, pregnant and lactating cats. | The safe use of Credelio in breeding, pregnant or lactating dogs hasn't been evaluated. | The safe use of Simparica has not been evaluated in breeding, pregnant, or lactating dogs. |
How long does it take to work | Kills 100% of fleas within 8 hours of application. | Credelio starts killing fleas within 4 hours of administration and kills over 99% of fleas within 8 hours of administration. | Begins to kill adult fleas within 3 hours and ticks within 8 hours of administration. |
Taste | Applied to skin | Beef-flavored chewable | Liver flavor |
Active Ingredient(s) | Fluralaner | Lotilaner | sarolaner |
RX Required |
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Dosage | |||
Usage |
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Video | Coming soon | Coming soon | Coming soon |
Vet Review | Flea control in cats is always challenging, not only in terms of safe products, but also in ease of application, and ultimately performance. Over the past several years the oral products like Bravecto and Nexguard have been highly effective for flea and tick control in dogs, as well as surprisingly other, unforeseen benefits such as treating, controlling and often curing previously frustrating Demodex mite infestations, and for much longer periods of time; 3 months of protection after one tablet. While the drug company has not come out with a similar oral formulation for cats, they have come out with a topical formulation, which also is labeled as effective for up to 3 months after one application. Obviously, handling one's kitty only once for a flea/tick treatment over 3 months is certainly welcome to most feline guardians. While I don't have lots of clinical experience with this product, reports from the field have found it highly effective in treated patients. As with many other products, it is also often important to treat the home environment, where 90 percent of the flea life cycle occurs. While the product is being reported as highly effective, I am concerned about using a product labeled for 3 months in cats after one use, especially if a sensitive feline patient suffers a reaction. Occasional reactions reported include transient irritation at the site of the product application, as well as occasional digestive and neurological reactions, which may be significant. While the product is highly effective for an extended period and easy to use, I would tend to reach for products that are shorter acting, although they will, of course, have to be applied or given more frequently. | Belonging to the latest generation of flea/tick parasiticides(known as Isoxazoline medications), these palatable, beef flavored chewable tablets kills fleas quite effective, with most adult fleas being killed within 8 hours. One of the downsides, as compared with Vectra 3D is that Credilio does not repel either fleas or ticks, and has no effect on biting mosquitoes, which are the main vectors that transmit heartworms to dogs. Credilio and products of its class are one of the most effective products against several species of severe disease transmitting ticks, including ones that transmit Lyme Disease, Ehrlichiosis, Rocky Mountain Spotted Fever and Anaplasmosis, which have been increasing in incidence in recent years. As with other members of this drug class, we have also used this drug in treatment and prevention of both demedex mites and scabies mites, although this is an off label use. Giving with a full meal reduces risks of digestive reaction. Overall the tablet is well tolorated, but occasional diarrhea, vomiting or digestive upset is seen. I would look to one of the other products like Vectra 3D, if there is a history of significant neurologic disease or seizures. I give this product an overall rating of a 4 out of 5. | Within the past few years, we have seen a surge of new flea and tick parasiticides for dogs and cats, especially important as we are discovering increased transmission of health-threatening disease to our animal companions. In the past year, the very trustworthy and reliable pharmaceutical company Zoetis has come out with a revolutionary liver flavored chewable tablet, Simparica, that is highly effective against fleas and multiple species of ticks. Compared to similar oral tablets, as well as other topical products, I find that Simparica works even more quickly than competitor products, starting to kill fleas within 3 hours, and ticks within 8 hours. Unlike other products labeled for monthly use, studies and my clinical experience show that Simparica is actually effective up to 35 days, not dropping off in efficacy as many other products do in killing fleas and ticks toward the end of the month. I also find that the many flexible dosing packages offer convenience to canine guardians, even in small dogs who weigh under 5 pounds. In addition to the efficacy against fleas and ticks, the product is also labeled effective against scabies mites. Many veterinarians and dermatologists are also now reaching for Simparica as a quick, safe and effective off-label treatment of demodex mange mites, which have long been very difficult to manage in veterinary medicine. I have found that in many cases one dose of Simparica will clear up many demodex mange cases within one month of the first pill. I have found that most dogs tolerate this product very well, especially when given with food. I have occasionally seen mild digestive upset in some sensitive pets, as well as rare neurological reactions. If a dog has a history of seizures, I would probably be cautious in using this product or ones of a similar class. Most dogs readily take this chewable tablet. I give this product an overall rating of a 4.5, with an efficacy of 4.5, and ease of use a 4.5. |