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Kills Fleas | |||
Repels Fleas | |||
Kills Flea eggs and Larvae | N/A | Prevents Development | |
Kills Ticks | |||
Repels Ticks | |||
Kills and/or Repels Mosquitoes | |||
Prevents Heartworm | |||
Other Parasites Information | N/A | Controls adult hookworms and removes and controls adult roundworms & whipworms | |
Waterproof (shampooing once a week can reduce effectiveness) | N/A | N/A | N/A |
Safe for pregnant or nursing Pets | The safe use of Advantus Oral Flea Treatment Soft Chews for Dogs in pregnant, breeding or lactating dogs has not been evaluated. | The safe use of Credelio in breeding, pregnant or lactating dogs hasn't been evaluated. | |
How long does it take to work | Effectively kills fleas within one hour of administration and is 96% effective against adult fleas within 4 hours. | Credelio starts killing fleas within 4 hours of administration and kills over 99% of fleas within 8 hours of administration. | Begins to work Immediately, However, pre-existing flea populations may continue to develop and emerge. |
Taste | Savory soft chew | Beef-flavored chewable | Beef Flavor |
Active Ingredient(s) | Imidacloprid | Lotilaner | Milbemycin Oxime/Lufenuron |
RX Required | |||
Dosage | |||
Usage | |||
Video | Coming soon | Coming soon | Coming soon |
Vet Review | There is now an excellent, overall safe oral chewable medication in the fight against flea infestation. This product, which has the same main ingredient as the topical product Advantage, that has been out for decades, may have an important place in a comprehensive flea control program. Especially during the warmer, summer months, the increased exposure to fleas and other parasites will often overwhelm existing products, thus occasionally allowing adult fleas to be seen on the pet. While many of the currently available products overall do an outstanding job in overall flea control, there can on occasion be brief lapses in flea control, where adult fleas may be seen. In these situations, as well as when guardians first discover flea infestations on pets, not on any preventative products, Advantus can fill the void. Most pets will readily accept these chewable wafers, which offers dramatic and quick kill of adult fleas. This quick kill of adult fleas will occur within minutes to an hour, and with almost all adult fleas gone within 4 hours, often before they have had the chance to lay eggs. This is especially important in those younger dogs under one year of age, who can quickly become severely anemic when overrun by adult flea exposure. Much easier to apply than shampoos, sprays, powders or collars, no product works as fast in my experience and opinion. Most pets tolerate the product very well, with only rare digestive upset seen. I have only seen ever more rare cases of neurological weakness. I also like the fact that this product can be used up to once daily as needed, which is especially important, while other, broader spectrum flea products that kill larvae and eggs are implemented in the flea control program. I give this product an overall rating of 4.5 with an ease of application/taste of 5 out of 5. | Belonging to the latest generation of flea/tick parasiticides(known as Isoxazoline medications), these palatable, beef flavored chewable tablets kills fleas quite effective, with most adult fleas being killed within 8 hours. One of the downsides, as compared with Vectra 3D is that Credilio does not repel either fleas or ticks, and has no effect on biting mosquitoes, which are the main vectors that transmit heartworms to dogs. Credilio and products of its class are one of the most effective products against several species of severe disease transmitting ticks, including ones that transmit Lyme Disease, Ehrlichiosis, Rocky Mountain Spotted Fever and Anaplasmosis, which have been increasing in incidence in recent years. As with other members of this drug class, we have also used this drug in treatment and prevention of both demedex mites and scabies mites, although this is an off label use. Giving with a full meal reduces risks of digestive reaction. Overall the tablet is well tolorated, but occasional diarrhea, vomiting or digestive upset is seen. I would look to one of the other products like Vectra 3D, if there is a history of significant neurologic disease or seizures. I give this product an overall rating of a 4 out of 5. | Sentinel is a wonderful combination of the heartworm prevention pill interceptor and the flea control product program both in this one pill. Many clients enjoy the convenience of having such broad acting internal and external parasites in one pill, without having to worry about giving two separate medicines. Lufenuron, which is the main flea control ingredient, stops the flea life cycle in its track at the egg and larval stage, thus being like a birth control pill for fleas who get on our pets. Given that the main problem of fleas is how rapidly they reproduce, this pill literally stops escalating growth of flea populations, before they can become established in our homes, where most of the flea life cycle occurs. The main disadvantage to this product is that it does not kill or repel adult fleas, so in situations with already established heavy infestations, it is best combined with a great topical product like advantage or front line or with the oral adulticide flea pill Capstar for maximal effect. The only other rare disadvantage I see is the slight increase in reactions when two products are combined into one like this, but fortunately this is not common in clinical practice. With milbemycin for prevention of heartworms and controlling and treating most common intestinal worms, I overall highly recommend this versatile product. |
Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors.
The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
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