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Kills Fleas |
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Repels Fleas |
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Kills Flea eggs and Larvae | N/A |
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Kills Ticks |
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Repels Ticks |
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Kills and/or Repels Mosquitoes |
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Prevents Heartworm |
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Other Parasites Information | N/A |
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Waterproof (shampooing once a week can reduce effectiveness) | N/A |
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N/A |
Safe for pregnant or nursing Pets | The safe use of Credelio in breeding, pregnant or lactating dogs hasn't been evaluated. | Consult your veterinarian | The safe use of Simparica has not been evaluated in breeding, pregnant, or lactating dogs. |
How long does it take to work | Credelio starts killing fleas within 4 hours of administration and kills over 99% of fleas within 8 hours of administration. | 1 day | Begins to kill adult fleas within 3 hours and ticks within 8 hours of administration. |
Taste | Beef-flavored chewable | Applied to Skin | Liver flavor |
Active Ingredient(s) | Lotilaner | Amitraz | sarolaner |
RX Required |
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Dosage | |||
Usage |
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Video | Coming soon | Coming soon | Coming soon |
Vet Review | Belonging to the latest generation of flea/tick parasiticides(known as Isoxazoline medications), these palatable, beef flavored chewable tablets kills fleas quite effective, with most adult fleas being killed within 8 hours. One of the downsides, as compared with Vectra 3D is that Credilio does not repel either fleas or ticks, and has no effect on biting mosquitoes, which are the main vectors that transmit heartworms to dogs. Credilio and products of its class are one of the most effective products against several species of severe disease transmitting ticks, including ones that transmit Lyme Disease, Ehrlichiosis, Rocky Mountain Spotted Fever and Anaplasmosis, which have been increasing in incidence in recent years. As with other members of this drug class, we have also used this drug in treatment and prevention of both demedex mites and scabies mites, although this is an off label use. Giving with a full meal reduces risks of digestive reaction. Overall the tablet is well tolorated, but occasional diarrhea, vomiting or digestive upset is seen. I would look to one of the other products like Vectra 3D, if there is a history of significant neurologic disease or seizures. I give this product an overall rating of a 4 out of 5. | This is one of my favorite and most effective products in preventing tick infestations on dogs of all sizes, as well as preventing the tick born diseases such as Lyme disease, Rocky Mountain Spotted Fever, Ehlrichia and Anaplasmosis. When some of the topical products have failed in some patients, I have found this collar quite valuable in significantly cutting down on tick burdens in these dogs. The effects are long lasting for up to 3 months preventing ticks from even attaching to dogs, and thus cutting down on tick exposure to humans as well. The only problems in terms of efficacy I have even seen with this product is when animal guardians apply the collar too loosely to their pets, which can cut down on its efficacy against ticks.. In order for this collar to work effectively, it must be fitted snugly against the pet's neck, where one is just able to get two fingers under the collar. If the collar is applied too loosely I have occasionally seen pets ingest this collar, leading to serious systemic reactions. The only other downside in using this collar is if the pet spends a significant time swimming during the warmer months. The collar's efficacy is cut down significantly if it is submerged in water or exposed to drenching rains. However when properly fitted to a dog's neck, this is one of the most effective products in preventing tick infestations on the market. | Within the past few years, we have seen a surge of new flea and tick parasiticides for dogs and cats, especially important as we are discovering increased transmission of health-threatening disease to our animal companions. In the past year, the very trustworthy and reliable pharmaceutical company Zoetis has come out with a revolutionary liver flavored chewable tablet, Simparica, that is highly effective against fleas and multiple species of ticks. Compared to similar oral tablets, as well as other topical products, I find that Simparica works even more quickly than competitor products, starting to kill fleas within 3 hours, and ticks within 8 hours. Unlike other products labeled for monthly use, studies and my clinical experience show that Simparica is actually effective up to 35 days, not dropping off in efficacy as many other products do in killing fleas and ticks toward the end of the month. I also find that the many flexible dosing packages offer convenience to canine guardians, even in small dogs who weigh under 5 pounds. In addition to the efficacy against fleas and ticks, the product is also labeled effective against scabies mites. Many veterinarians and dermatologists are also now reaching for Simparica as a quick, safe and effective off-label treatment of demodex mange mites, which have long been very difficult to manage in veterinary medicine. I have found that in many cases one dose of Simparica will clear up many demodex mange cases within one month of the first pill. I have found that most dogs tolerate this product very well, especially when given with food. I have occasionally seen mild digestive upset in some sensitive pets, as well as rare neurological reactions. If a dog has a history of seizures, I would probably be cautious in using this product or ones of a similar class. Most dogs readily take this chewable tablet. I give this product an overall rating of a 4.5, with an efficacy of 4.5, and ease of use a 4.5. |