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Reduces Pain and Inflammation associated with Arthritis? |
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Reduces Fever? |
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Reduces Joint Stiffness? |
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Controls Symptoms of Osteoarthritis |
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Additional Benefits | Targets canine osteoarthritis pain and inflammation while reducing the impact on GI, kidney, and liver homeostasis. | Also relieves pain and inflammation from hip dysplasia |
What Makes it Different? | Galliprant (grapiprant tablets) is a first-in-class non-COX-inhibiting prostaglandin receptor antagonist. It specifically blocks the EP4 receptor, the primary mediator of canine osteoarthritis pain and inflammation. Galliprant (grapiprant tablets) does not inhibit the production of many housekeeping prostanoids that maintain homeostatic functions. | Generic equivalent to Rimadyl, comes in chewable tablet or caplet form |
Recommended For? | Dogs (9 months of age or older, weighing 8 lbs or more) | Dogs (Over 6 weeks of age) |
Product Type | Tablet | Chewable Tablet |
Usage |
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RX Required |
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How Long does it Take to Work? | Within Hours of Dose | Within Hours of Dose |
Video | ||
Ingredients | Grapiprant | Carprofen |
Does it have long-term side effects? | In a 9-month toxicity study, vomiting and soft-formed or mucus stool were observed in all groups, including controls, with higher incidence in grapiprant-treated dogs. Decreases in serum albumin and total protein were seen with increasing doses of grapiprant. Hypoalbuminemia and hypoproteinemia were reversible when treatement was discontinued. Three treated dogs and one control dog had elevated alkaline phosphatase values. | Laboratory studies in anesthetized dogs and clinical field studies have demonstrated that carprofen is well tolerated in dogs after oral administration. |
Cautions | Galliprant (grapiprant tablets) is for use in dogs 9 months of age or older, weighing 8 lbs or more only. Do not use in cats. Galliprant (grapiprant tablets) are not for use in humans. Keep this and all medications out of reach of children and pets. Consult a physician in case of accidental ingestion by humans. Store Galliprant (grapiprant tablets) out of reach of dogs and other pets in a secured location in order to prevent accidental ingestion or overdose. | Contact the veterinarian if the pet has bloody, black or tarry stools, blood in vomit, or swelling or rapid weight gain due to fluid retention. Do not use on cats. |
What are Customers saying Pros | I cannot say enough how great this med is. My lab’s pain was so bad that I thought she had experienced a stroke…..she couldn’t walk without help, and her face and eyes showed confusion and pain. After one pill, she began to feel better and in less than 24 hours she was back to her normal self. I was afraid I was going to lose her, but this med has brought her back to me. It is a miracle worker. | My poor old Lady and I share problems getting up and down ... the Novox has really helped her. Wish I could take some! (Just kidding, of course.) It really has made a difference in her mobility - and her disposition. Thanks! |
What are Customers saying Cons | From a helping stand point it's perfect; he’s so much better…from a money standpoint, saddening this is so expensive. | ...will not take Novox...I don't know if it has a bitter taste..."...may cause kidney failure. |
Vet Recommendations | There has been an exciting development in the area of pain management in the past year. The recognition, understanding, and use of pain management medications in veterinary medicine has grown dramatically, especially for osteoarthritis in dogs. Over the past 20 years, improved nonsteroidal anti-inflammatory medications such as Rimadyl, Metacam, Deramaxx, and Previcox, have indeed been great helps in managing pain and inflammation in arthritic patients, however, there remain risks in occasional, sensitive animals of serious side effects, whether it be on the digestive tract, kidneys or liver. With the arrival of the new drug Galliprant, conventional veterinarians now have a unique and innovative product that targets the clinical signs(i.e pain, inflammation) of arthritis by specifically blocking a particular receptor, while sparing other similar receptors to continue, do help with balance and health. Therefore there are much fewer risks of especially kidney and liver dysfunction. While GI side effects can occasionally occur, they are much rarer and milder than with many nonsteroidal anti-inflammatory medications and can be minimized by giving with food. The medication starts working within the day, but more typical is gradual improvement over the first month of therapy. While veterinarians are still gaining clinical experience in this newly approved drug, the main side effect rarely encountered is short lived vomiting, which typically resolves on its own. Even rarer are loose, mucoid stools. An outstanding benefit of this novel product is that it can be used in animals as young as one year of age. It also comes in a very palatable pork liver flavor formulation. I give this medication an overall rating of a 4.5. | Currently under review |