NEW CUSTOMERS SAVE 40% W/AUTOSHIPUse code NEW40 (Up to $30 max. Exclusions apply)
SAVE AN EXTRA $5 - $20 OFFUse code PETS in cart (Exclusions apply)
Kills Fleas |
![]() |
![]() |
![]() |
Repels Fleas |
![]() |
![]() |
![]() |
Kills Flea eggs and Larvae |
![]() |
![]() |
![]() |
Kills Ticks |
![]() |
![]() |
![]() |
Repels Ticks |
![]() |
![]() |
![]() |
Kills and/or Repels Mosquitoes |
![]() |
![]() |
![]() |
Prevents Heartworm |
![]() |
![]() |
![]() |
Other Parasites Information | NA | Treats and controls hookworms, roundworms, and whipworms infections. | |
Waterproof (shampooing once a week can reduce effectiveness) |
![]() |
NA | N/A |
Safe for pregnant or nursing Pets |
![]() |
Consult with your veterinarian before using this product on debilitated, aged, pregnant or nursing animals. | Consult your veterinarian |
How long does it take to work | Reapply every 30 days. | Starts killing fleas in 30 minutes, and kills 98-100% of fleas in 12 hours. | Starts to kill fleas within 30 minutes; kills 100% of fleas within 4 hours. |
Taste | Applied to skin | Topical application | Beef Flavor |
Active Ingredient(s) | Indoxacarb, Permethrin | Spinetoram | Spinosad/Milbemycin Oxime |
RX Required |
![]() |
![]() |
![]() |
Dosage | |||
Usage |
![]() |
![]() |
![]() |
Video | Coming soon | Coming soon | Coming soon |
Vet Review | When the Activyl product line came out several years ago, it was touted as a totally novel new product on the market that would not have the problems of emerging flea resistance to products that has believed to been increasing in recent years with the old standby products in some cases. It supposedly works through a unique process of bioactivation using only the flea enzymes in activating the main ingredient, indoxacarb, in killing fleas. Along with the permethrin ingredient for tick coverage and control, it would seem like this would be a first line or excellent choice for those looking for a novel and comprehensive flea/tick product for their dogs. And while it is also effective in preventing flea eggs and larvae from developing as well, and can be highly effective in today's war against fleas and ticks, I have seen occasional problems with this product, as reported by clients. While its deeper penetration in the fatty oils of the skin may be a benefit, and while the product is not reported to be absorbed systemically, I have seen occasional and severe side effects reported by animal guardians. As with most other topical products in this venue, this particular product can occasionally cause irritation and itching at the site of application, which while usually only transient for a day or two, in some pets the itching and allergic reaction has been noted to intensify, necessitating anti-itch medications for relief. Some clients have also reported an odd odor from the application site for a while, as well as an oily film, which may persist for a few days. While many clients do report this product highly effective when other competitor products may have failed them recently, these occasional reactions are important to note, especially in a very sensitive or geriatric animal, and/or one with a chronic medical condition. On very rare occasions, clients have reported digestive side effects, as well as rare neurological weakness, stiffness or even spasms. While the vast majority of clients are satisfied with this product's performance and reliability, the decision on using this stronger, newer way of flea and tick control, should be made after careful consideration of patient history, as well as discussion with the local veterinarian. I give this product an overall rating of a 4, with an ease of use of a 5, with a mid-rating safety level of 3. | Fleas are easily the most common external parasite that plague cats throughout the country. Fleas have been shown to not only cause weakness and anemia in affected cats, but also transmit dangerous infectious diseases, including bartonellosis, an also increasing threat to humans. Cheristin is made with the same main ingredient as Comfortis for cats, and acts uniquely on the nervous system of the flea. Unlike flea prevention tablets, Cheristin starts killing fleas within 30 minutes and almost 100 percent of fleas within 12 hours. With the easy to use applicator, this product has been shown to be quite effective for one month. The most common, yet rare side effect I have seen in cats is an allergic reaction or hair loss at the site of application, and even less commonly vomiting and lethargy. It is an excellent and fast acting, effective product with an overall rating of a 4.5 with an ease of administration of a 5. | An exciting and brand new product now available combines the main ingredient of Interceptor milbemycin with a powerful flea insecticide known as spinosad. Given as a once monthly heartworm preventative, this product also will control and prevent whipworms, hookworms and roundworms, in addition to preventing heartworms. The additional ingredient spinosad allows effective flea and these internal parasite control all in one pill, making it quite convenient for clients. As with any pesticide rare digestive tract and neurological side effects may occur but this has not been a major problem in clinical trials. Since it is relatively new I will have to see how this product performs on the fleas but it seems to have excellent potential. I give this product an overall rating of a 5 with an ease of administration a 5 as well, taste a 5. |