Advantage Multi vs. Centragard Comparison

Advantage Multi

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Centragard

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Revolution Plus for Cats

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Prevents Heartworm Disease

Roundworms

Hookworms

Whipworms

Tapeworms

Fleas

Yes, Adult

Other Parasites

Treats and controls ear mite infestations

Kills 3 species of ticks commonly found in cats, and treats and controls ear mites.

Safe for Breeding, Pregnant or Nursing Pets

Safety has not been established in breeding, pregnant, or lactating cats.

N/A

Age/Weight Requirements

9 weeks of age or older and weighing at least 2 lbs

7 weeks of age or older weighing at least 1.8 lbs

8 weeks of age or older, weighing at least 2.8 lbs

Rx Prescription Required

Dosage

Monthly

Usage

Video

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Veterinarian Review (Michael Dym, VMD)

By combining imidacloprid and moxidectin, advantage multi offers the wonderful benefit of broad protection against BOTH common internal and external parasites in dogs and cats. An important area of coverage includes not only adult stages, but the immature stages of roundworms and hookworms, two parasites that are a risk to people if not prevented in our pets. It also treats and controls, and prevents whipworms, which are difficult to eradicate in both dogs and the environment. When applied monthly, it is almost 100 percent effective in preventing heartworm disease in dogs and cats. Additional benefits of treating scabies and demodectic mange and ear mites make this a very attractive product. All of this with the wonderful flea control benefits of the product advantage. The greatest benefit I see with this versatile product is that it takes the labor out of administering a myriad of medications to dogs to control these varied internal and external parasites. I also find that it kills the larval stages of fleas in the home surroundings of treated pets, which is a wonderful added benefit. I have on rare occasions seen topical irritation and sensitivity at the site of application, and even more scarse neurological reactions in hypersensitive pets. The only other downside would be the potential high cost of this product, as well as the need for clients to obtain a prescription from their veterinarian. Overall, however, I have found this product to be an excellent and safe all around internal and external parasite control manager in our dogs and cats.

This new product on the market launched in August, 2018 comes at a time when the American Heartworm Society is warning that one in 4 cats diagnosed with heartworms are indoor only cats, thus necessitating veterinarians to carefully examine the issue of recommending not only year round heartworm pevention in dogs, but also in cats, especially in southern, warmer climates. This product is a wonderful general and very broad spectrum parasiticide control product to use in cats, which when applied topically, circulates in the blood and is wonderful at preventing hookworms, round worms and heartworms in cats, as well as treating tapeworms with the inclusion of praziquantel. Tapeworms are a very frustrating parasite that is often difficult to control, especially in outdoor cats, and often recurs weeks to months after effective treatment. With the inclusion of the praziquantel in this monthly applied product, tapeworm control is close to 100 percent, eliminating those unsightly moving rice like worms near a cat's tail or anus, so a great product to use in outdoor cats where heartworm, flea and internal parasite protection are priorities. A downside with this product is that it does not control fleas or ticks. . Rare side effects in sensitive cats include drooling and/or occasional vomiting, especially if licked off, and occasional clumping of hair or skin irritation at the site of application. Even more rare are neurological reactions, but I have only seen this when the product is licked off when applied inappropriately. I give this product an overall rating of a 4 out of 5 with an ease of application of a 4.

A significant limitation of the original revolution product for cats is that it did not cover any species of ticks, which is especially important in those cats who go outside and/or live with dogs where there is increased chance of tick borne infections such as Lyme disease, Ehrlichia and Anaplasmosis in dogs, not to mention the risk of tick born disease exposure in people whose cats bring ticks in to the home. With this new formulation clients get protection against 3 species of ticks. The American Heartworm Society has published that one in 4 cats diagnosed with heartworm disease are indoor only cats, so that especially in Southern, warmer clients, heartworm disease prevention may become as important in cats as dogs. And it takes only a few heartworms to cause significant disease in cats, who seem much more sensitive on exposure to this parasite than even dogs are. This versatile product not only kills fleas before they eggs, but gives additional 6 in 1 protection again ticks, round worms, hookworms, as well as ear mites. THe product is quite quick drying, easy to apply, and not messy or greasy like many other topical formulations. The only down side as to efficacy is in those cases where there is a severe flea infestation affecting multiple animals in a household, where I have found some of the other products a bit more effective in those cases in both dogs and cats, however the vast majority of flea infestations are easily taken care of with this product. Because of the addition of the Sarolamer ingredient for tick control, I would not use this product if there is any history of neurological disease or seizures in the cat. The only other rare side effect I have seen is lethargy and because of its easy to use formulation, only very rare contact sensitivity. With all this being said, I give this product an overall rating of a 4 out of 5 with an ease of application of 5.

Our expert panel consists of licensed veterinarians and the knowledgeable staff of PetMed Express, Inc. d/b/a 1-800-PetMeds. Neither the Company nor any of its employees or consultants make any warranties, expressed or implied, or representations about the accuracy or completeness of the content or the content of any site or external sites. Likewise, no legal liability or responsibility is assumed for the accuracy or completeness of any information, or usefulness of products discussed. While every effort has been made to accurately represent the qualities and characteristics of each product, which for the most part were taken directly from the websites of the manufacturers, we are not responsible for any errors. The information presented is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian. Note: Any trademarks are the property of their respective companies.