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Proin (phenylpropanolamine hydrochloride) - Urinary Incontinence Chewable Tablets for Dogs

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About this product

What is Proin?

Proin is a medication that is used to relieve the symptoms of urinary incontinence in dogs. Proin requires a prescription from your veterinarian who is in the best position to evaluate if your pet will benefit from using this drug.

For:

Dogs

Benefits:

  • Is a supplement for urinary incontinence in dogs
  • Ensures sustained phenylpropanolamine levels in the blood stream and may help reduce the conditions often associated with high levels of phenylpropanolamine such as: decreased appetite, changes in heart rate, increased blood pressure, hyperexcitability

How it Works:

Proin contains the active ingredient phenylpropanolamine, an adrenergic agent that works by tightening the bladder sphincter muscle, which helps to control urine leakage.

Cautions:

Don't give Proin with ephedrine or epinephrine, and don't give it within two weeks of using a MAOi, such as Anipryl, selegiline or a Preventic Collar. Possible side effects can occur, including restlessness, or loss of appetite, difficulty breathing, hives, and swelling of the lips, tongue, or face. If these or any other side effects occur, contact your veterinarian immediately.

Brand Name:

Proin (PRN Pharmacal)

Generic Name:

Phenylpropanolamine

What is the most important information I should know about Proin:

Proin is a prescription medication for veterinary use in dogs. Proin is available as 25mg, 50mg and 75mg chewable, liver flavor tablets. Proin may cause restlessness, irritability, or loss of appetite.

What is Proin:

Proin is an adrenergic agent used as a supplemental product for urinary incontinence in dogs. Proin may also be used for purposes other than those listed in this guide.

What should I discuss with my veterinarian before giving Proin to my pet:

Tell your veterinarian if your pet has ever had an allergic reaction to this medication. Tell your veterinarian if your pet has glaucoma, hyperthyroid disease, diabetes, heart problems or high blood pressure. Tell your veterinarian if your pet is pregnant or lactating.

How should this medication be given:

The usual dose for dogs is 0.4-0.8mg/pound every 12 hours. Give Proin exactly as directed by the veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store Proin at room temperature away from moisture and heat. Keep this medication away from children and pets. 

What happens if I miss giving a dose:

Give the missed dose as soon as you remember during the same day. However, if you don't remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.

What happens if I overdose my pet:

Seek emergency veterinary medical treatment. Symptoms of overdose may include increased blood pressure, increased heart rate, seizures or coma.

What should I avoid while giving Proin to my pet:

Do not give Proin with ephedrine or epinephrine and do not give within 2 weeks of using an MAOi such as selegiline or Preventic Collar.

What are the possible side effects of Proin:

Stop giving Proin and contact your veterinarian immediately if your pet has an allergic reaction (difficulty breathing; swelling of the lips, tongue, face; and hives). Other side effects that may occur include restlessness, irritability, increased heart rate, increased blood pressure and loss of appetite. Continue to give the medication and contact your veterinarian. Other less serious side effects may occur. Contact your veterinarian about any side effects that seem bothersome.

What other drugs will affect Proin:

Before giving Proin, tell your veterinarian if your pet is being given digoxin, NSAIDs such as aspirin or Rimadyl, tricyclic antidepressants such as clomipramine, and beta blockers such as atenolol, or any other prescription or over the counter medications. 

Where can I get more information:

Your pharmacist has additional information about Proin written for health professionals that you may read.

See more

Proin Directions:

  • Proin liver flavored chewable tablets are available by prescription for use in dogs to treat urinary incontinence.
  • Proin may cause restlessness, irritability, or loss of appetite.
  • Tell your veterinarian about any other medication you may be giving your pet.
Tip:

Give this medication exactly as directed by your veterinarian. Do not exceed 1.8mg/lb per day. The medication may be given with food.

Proin Dosage for Dogs:

Dogs:
WeightDosage
All weightsThe usual dose for dogs is 0.4-0.8mg/pound every 12 hours.
Proin Dosage for Cats:
Cats
Do not use!
Proin Dosage for Horses:
Horses
Do not use!

Storage:

Should be stored at room temperature away from moisture and heat. Keep this medication away from children and pets.

Proin Ingredients:

Proin Chewable Flavor Tabs 25 mg
Active IngredientsStrength
Phenylpropanolamine25 mg
Proin Chewable Flavor Tabs 50 mg
Active IngredientsStrength
Phenylpropanolamine50 mg
Proin Chewable Flavor Tabs 75 mg
Active IngredientsStrength
Phenylpropanolamine75 mg
Product Details
plus minus

What is Proin?

Proin is a medication that is used to relieve the symptoms of urinary incontinence in dogs. Proin requires a prescription from your veterinarian who is in the best position to evaluate if your pet will benefit from using this drug.

For:

Dogs

Benefits:

  • Is a supplement for urinary incontinence in dogs
  • Ensures sustained phenylpropanolamine levels in the blood stream and may help reduce the conditions often associated with high levels of phenylpropanolamine such as: decreased appetite, changes in heart rate, increased blood pressure, hyperexcitability

How it Works:

Proin contains the active ingredient phenylpropanolamine, an adrenergic agent that works by tightening the bladder sphincter muscle, which helps to control urine leakage.

Cautions:

Don't give Proin with ephedrine or epinephrine, and don't give it within two weeks of using a MAOi, such as Anipryl, selegiline or a Preventic Collar. Possible side effects can occur, including restlessness, or loss of appetite, difficulty breathing, hives, and swelling of the lips, tongue, or face. If these or any other side effects occur, contact your veterinarian immediately.

Brand Name:

Proin (PRN Pharmacal)

Generic Name:

Phenylpropanolamine

What is the most important information I should know about Proin:

Proin is a prescription medication for veterinary use in dogs. Proin is available as 25mg, 50mg and 75mg chewable, liver flavor tablets. Proin may cause restlessness, irritability, or loss of appetite.

What is Proin:

Proin is an adrenergic agent used as a supplemental product for urinary incontinence in dogs. Proin may also be used for purposes other than those listed in this guide.

What should I discuss with my veterinarian before giving Proin to my pet:

Tell your veterinarian if your pet has ever had an allergic reaction to this medication. Tell your veterinarian if your pet has glaucoma, hyperthyroid disease, diabetes, heart problems or high blood pressure. Tell your veterinarian if your pet is pregnant or lactating.

How should this medication be given:

The usual dose for dogs is 0.4-0.8mg/pound every 12 hours. Give Proin exactly as directed by the veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store Proin at room temperature away from moisture and heat. Keep this medication away from children and pets. 

What happens if I miss giving a dose:

Give the missed dose as soon as you remember during the same day. However, if you don't remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.

What happens if I overdose my pet:

Seek emergency veterinary medical treatment. Symptoms of overdose may include increased blood pressure, increased heart rate, seizures or coma.

What should I avoid while giving Proin to my pet:

Do not give Proin with ephedrine or epinephrine and do not give within 2 weeks of using an MAOi such as selegiline or Preventic Collar.

What are the possible side effects of Proin:

Stop giving Proin and contact your veterinarian immediately if your pet has an allergic reaction (difficulty breathing; swelling of the lips, tongue, face; and hives). Other side effects that may occur include restlessness, irritability, increased heart rate, increased blood pressure and loss of appetite. Continue to give the medication and contact your veterinarian. Other less serious side effects may occur. Contact your veterinarian about any side effects that seem bothersome.

What other drugs will affect Proin:

Before giving Proin, tell your veterinarian if your pet is being given digoxin, NSAIDs such as aspirin or Rimadyl, tricyclic antidepressants such as clomipramine, and beta blockers such as atenolol, or any other prescription or over the counter medications. 

Where can I get more information:

Your pharmacist has additional information about Proin written for health professionals that you may read.

See more
How to use
plus minus

Proin Directions:

  • Proin liver flavored chewable tablets are available by prescription for use in dogs to treat urinary incontinence.
  • Proin may cause restlessness, irritability, or loss of appetite.
  • Tell your veterinarian about any other medication you may be giving your pet.
Tip:

Give this medication exactly as directed by your veterinarian. Do not exceed 1.8mg/lb per day. The medication may be given with food.

Proin Dosage for Dogs:

Dogs:
WeightDosage
All weightsThe usual dose for dogs is 0.4-0.8mg/pound every 12 hours.
Proin Dosage for Cats:
Cats
Do not use!
Proin Dosage for Horses:
Horses
Do not use!

Storage:

Should be stored at room temperature away from moisture and heat. Keep this medication away from children and pets.

Ingredients
plus minus

Proin Ingredients:

Proin Chewable Flavor Tabs 25 mg
Active IngredientsStrength
Phenylpropanolamine25 mg
Proin Chewable Flavor Tabs 50 mg
Active IngredientsStrength
Phenylpropanolamine50 mg
Proin Chewable Flavor Tabs 75 mg
Active IngredientsStrength
Phenylpropanolamine75 mg
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4547 Gods Will
today
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Breed Welsh Springer Spaniel
Worth the money!!
My aging dog is able to make it long enough to make it to outside to potty. Great deal of improvement since being placed on Proin. It was easy to adjust to find the right dosage.
Helpful?
Donna
today
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Breed American Straffordshire Terrier/German Shepherd
Works!
CoCo has been on the tablets for about 4 years. It's made all the difference in our lives. Indeed, I suspect the previous owners gave her up because of her pee issue, likely thinking she was doing it intentionally rather than because her spay operation.
Helpful?
Pretty Penny
4 months ago
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Breed Great Pyrenees- Bernese Mix
Great product
It took a few months to get the dose right but she’s a large growing dog. I think we have it right now. I will need to start shipping to my offices because the drug requires a signature and we work during the day. Had to chase the UPS truck down. Otherwise we will be taking it the rest of her life so glad to set it up for auto ship.
Helpful?
JohnG85
5 months ago
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Breed Labradoodle
Proin
Tilda has been on Proin for years and doing great. Only problem is your shipping is too slow.
Helpful?
Cassie
5 months ago
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Breed Mix
Helpful?
Jean
5 months ago
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Breed Lab mix
Proin immediately took care of Sage’s occasional incontinence issues.
Review photo
Helpful?
hddenver1
5 months ago
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Breed GSP’s
Awesome Customer Service
It is pure pleasure dealing with Pet Meds. They always step up to plate when it comes to insuring my puppies have medications. Thank You!
Helpful?
Daniel
10 months ago
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Breed Yellow Lab
Dr. Changed his mind, now PROIN ER
I have used PROIN for years and it has been great. Now she is leaking a little bit. The Dr. has switched to PROIN ER and it is working fine.
Helpful?
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